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Dr. Daniel Pompa

What Causes Thyroid Problems

What Causes Thyroid Problems – Getting To The Cause Of The Issue

Let’s look at exactly what causes thyroid problems. The most common cause of thyroid issues is an autoimmune disorder known as Hashimoto’s disease. This occurs when the body’s immune system mistakenly attacks and destroys the cells in the thyroid gland, resulting in an underactive thyroid known as hypothyroidism. Other causes include Graves’ Disease, iodine deficiency, selenium deficiency, vitamin deficiencies, pregnancy, radiation exposure, certain medications, and genetic abnormalities.

Approximately 27 million people in the United States are afflicted by thyroid disorders, and shockingly, 13 million of these individuals remain unaware that they have a thyroid-related issue. Thyroid disorder is recognized as the most under-diagnosed condition in the country, with an estimated 4.6% of U.S. citizens aged 12 and above suffering from hypothyroidism, wherein the thyroid becomes underactive.1 2

How Do I Know If I Have A Thyroid Problem?

Symptoms of a thyroid disorder include changes in weight, fatigue, dry skin, hair loss, constipation, depression, brittle nails, sensitivity to cold or heat, increased heart rate, and irregular menstrual cycles.3

Diagnosing thyroid disorders typically begins with a TSH blood test. While this method allows for the detection of many thyroid problems, it may not detect issues until TSH levels have drastically changed. This could mean that you suffer from the symptoms of a thyroid disorder for years before finally receiving an accurate diagnosis. Your doctor may insist that all is well during this time, even though you may still be experiencing symptoms. For this reason, it is important to stay aware of your body and watch out for any changes that could indicate a thyroid disorder.

What Causes Thyroid Problems – Autoimmune Diseases

Autoimmune diseases such as Hashimoto’s thyroiditis and Grave’s disease are often responsible for thyroid problems. In these conditions, the body’s immune system mistakenly attacks the thyroid gland, resulting in inflammation that impairs its ability to function properly.4 5

Another cause of thyroid problems is that T4, also known as thyroxine, is not able to be converted into T3, the active form of thyroid hormone. If T4 is unable to convert to T3, the message it is carrying cannot be relayed to cells even if there is a high amount of T4 circulating in the blood. This means that the typical treatment, Synthroid (T4), doesn’t correct the problem.

The conversion of T4 into T3 takes place in the liver. When the liver is under extreme stress, it produces an alternate form of the thyroid hormone T3 known as reverse T3 (rT3). This form of the hormone binds to cell thyroid receptors and prevents T3 from binding to them, thus blocking its message from being transmitted to cells.6

What Causes Thyroid Problems - Autoimmune Diseases

What Causes Thyroid Problems – Environmental Toxins

Environmental toxins can also contribute to the development of thyroid problems. Toxins such as lead, mercury, arsenic, manganese, and cadmium can disrupt the functioning of the thyroid. These heavy metals are all known endocrine disruptors that can alter hormone levels and cause inflammation in the body. Exposure to these environmental toxins may impede normal thyroid functioning and cause hypothyroidism, hyperthyroidism, and other thyroid problems.7 8

Additionally, pesticides, herbicides, dioxins, PCBs, and other chemicals that are sprayed in the environment can also affect the body’s hormones and cause thyroid imbalances. It is important to reduce exposure to these toxins whenever possible in order to help maintain healthy thyroid function.9

Read more about toxins in our environment.

What Causes Thyroid Problems – Genetic Predisposition

Certain genetic conditions may increase the risk of thyroid disease. In some cases, individuals inherit a thyroid disorder from their family members or have an autoimmune condition that affects the thyroid gland. Having a close family member who has had thyroid issues increases the risk of developing a thyroid disorder for yourself. Additionally, some people may have an inherited tendency to develop autoimmune conditions which can increase the risk of developing thyroid problems.10

What Causes Thyroid Problems – Iodine Deficiency

Iodine deficiency is a major cause of thyroid problems. Iodine is an essential mineral that plays a critical role in the production of thyroid hormones in the body. Without sufficient iodine, the thyroid cannot produce enough hormones to keep the body functioning normally, leading to hypothyroidism.

A lack of iodine can also lead to goiter, which is an enlargement of the thyroid. Goiter can occur when the body does not have enough iodine to produce hormones. The most common form of goiter is endemic goiter, which is caused by a lack of iodine in the diet.

In areas where there is insufficient access to iodized salt or seafood, people are at risk for developing iodine deficiency and related thyroid problems. It is important to consume a diet that contains foods rich in iodine, such as seafood, seaweed, dairy products, and eggs. Additionally, supplementation with iodine may be necessary for individuals who are unable to get enough from their diets.11

What Causes Thyroid Problems - Iodine Deficiency

What Causes Thyroid Problems – Selenium Deficiency

Selenium deficiency is a common cause of thyroid problems. As a trace mineral, selenium is necessary for our bodies to produce certain enzymes and hormones that are essential for the proper functioning of the thyroid gland. When there’s not enough selenium present in the body, the production of these compounds can be impaired, resulting in an array of thyroid-related symptoms such as fatigue, depression, weight gain, and difficulty concentrating.

Selenium can be found naturally in many foods, but it’s not always easy to get enough of it through diet alone. Those who are at risk for selenium deficiency include people on vegetarian or vegan diets, those with gastrointestinal disorders like celiac disease or Crohn’s disease, and those taking certain medications that interfere with the absorption of selenium. If you think you may be deficient in selenium, supplement or better yet, increase your intake of foods high in selenium, like Brazil nuts, tuna, and mushrooms. Selenium is an essential mineral for overall health and should not be ignored if you’re dealing with thyroid issues.12

What Causes Thyroid Problems – Vitamin D Deficiency

One of the most common causes of thyroid problems is vitamin D deficiency. Vitamin D helps to regulate the production of hormones in the thyroid gland. A lack of vitamin D can also cause fatigue, depression, bone loss, autoimmune diseases, and other health issues.13

To prevent a vitamin D deficiency, it’s important to get adequate amounts of sunlight each day. Additionally, eating foods high in vitamin D such as fatty fish, eggs, and mushrooms can help to keep levels up.

Read more about how important adequate vitamin D intake is.

What Causes Thyroid Problems – Vitamin B12 Deficiency

Vitamin B12 deficiency also causes thyroid problems. Vitamin B12 plays an important role in hormone production, including the hormones that help regulate your metabolism. When you don’t get enough B12, your body can’t make enough thyroid hormone, leading to hypothyroidism and other related health issues. A lack of B12 can also create an imbalance in other hormones, further contributing to thyroid problems.

Certain medical conditions such as pernicious anemia or celiac disease can make it difficult for the body to absorb enough B12 from food sources. Additionally, taking certain medications over a long period of time can lead to a vitamin B12 deficiency. If a vitamin B12 deficiency is diagnosed, supplementation can help reverse the symptoms associated with thyroid problems.14

What Causes Thyroid Problems - Vitamin B12 Deficiency

What Causes Thyroid Problems – Iron Deficiency

Iron deficiency can cause thyroid problems. Iron helps the body make red blood cells which carry oxygen and other nutrients to the cells in our body, including those in the thyroid gland. When iron levels are low, it causes a decrease in red blood cell production, which can lead to hypothyroidism. Anemia caused by iron deficiency can also cause a person to become fatigued, have difficulty concentrating, and even gain weight due to a slow metabolism. 

Additionally, it’s important to make sure that the diet contains adequate amounts of iron-rich foods such as lean red meat, fish, nuts and seeds, and dark green leafy vegetables. If an iron deficiency is not identified and treated, it can lead to more serious health problems such as heart failure or even death.15

Read more about common vitamin and mineral deficiencies.

What Causes Thyroid Problems – Microbiome Dysfunction

The human microbiome is composed of trillions of microorganisms that inhabit the body and play a role in regulating metabolism, digestion, and other functions. Recent research suggests that microbiota dysregulation may play an important role in the development of thyroid problems.16

Dysbiosis, or an imbalance of beneficial and pathogenic bacteria, can cause inflammation in the gut which can lead to autoimmune conditions and disrupt the functioning of the thyroid gland. Additionally, dysbiosis can lead to increased intestinal permeability or “leaky gut” which allows toxins, bacteria, and other microorganisms to enter the bloodstream and trigger an immune response leading to inflammation in other parts of the body including the thyroid.

Read more about Leaky Gut Syndrome.

What Causes Thyroid Problems - Microbiome Dysfunction

What Causes Thyroid Problems – Pregnancy-Related Issues

Pregnancy can also be a major cause of thyroid problems. During pregnancy, the body’s immune system may become suppressed, which can lead to an overactive or underactive thyroid gland. Changes in hormones during pregnancy can also contribute to thyroid issues, and they can affect both mother and baby. 

Common conditions related to pregnancy include Graves’ disease and Hashimoto’s disease. In addition, some pregnant women may develop postpartum thyroiditis, a condition in which the thyroid gland becomes inflamed after giving birth. This condition can cause symptoms of both hyperthyroidism and hypothyroidism that usually last for about 6 to 12 months.17

What Causes Thyroid Problems – Getting To The Cause Of The Issue

Now that you know what causes thyroid problems, there are many factors that you have control over. A lifestyle change that focuses on staying away from environmental toxins, as well as consuming sufficient iodine, selenium, vitamin D, iron, and vitamin B12 through a healthy diet like my Cellular Healing Diet can reduce the risk of developing thyroid-related conditions.

Read more about my Cellular Healing Diet.

References

1 Hypothyroidism (Underactive Thyroid). (2022, November 16). National Institute of Diabetes and Digestive and Kidney Diseases. https://www.niddk.nih.gov/health-information/endocrine-diseases/hypothyroidism

2 Blackwell J. Evaluation and treatment of hyperthyroidism and hypothyroidism. J Am Acad Nurse Pract. 2004 Oct;16(10):422-5. doi: 10.1111/j.1745-7599.2004.tb00418.x. PMID: 15543918.

3 Thyroid Disorders. (2022, October 28). Johns Hopkins Medicine. https://www.hopkinsmedicine.org/health/conditions-and-diseases/disorders-of-the-thyroid

4 Hashimoto’s Disease. (2022, November 16). National Institute of Diabetes and Digestive and Kidney Diseases. https://www.niddk.nih.gov/health-information/endocrine-diseases/hashimotos-disease?dkrd=hispt0297

5 American Thyroid Association. (2020, June 8). Graves’ Disease | American Thyroid Association. https://www.thyroid.org/graves-disease/

6 Peeters RP, Visser TJ. Metabolism of Thyroid Hormone. [Updated 2017 Jan 1]. In: Feingold KR, Anawalt B, Boyce A, et al., editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK285545/

7 Porterfield SP. Vulnerability of the developing brain to thyroid abnormalities: environmental insults to the thyroid system. Environ Health Perspect. 1994 Jun;102 Suppl 2(Suppl 2):125-30. doi: 10.1289/ehp.94102125. PMID: 7925183; PMCID: PMC1567088.

8 Aalami AH, Hoseinzadeh M, Hosseini Manesh P, Jiryai Sharahi A, Kargar Aliabadi E. Carcinogenic effects of heavy metals by inducing dysregulation of microRNAs: A review. Mol Biol Rep. 2022 Dec;49(12):12227-12238. doi: 10.1007/s11033-022-07897-x. Epub 2022 Oct 21. PMID: 36269534.

9 Porterfield SP. Vulnerability of the developing brain to thyroid abnormalities: environmental insults to the thyroid system. Environ Health Perspect. 1994 Jun;102 Suppl 2(Suppl 2):125-30. doi: 10.1289/ehp.94102125. PMID: 7925183; PMCID: PMC1567088.

10 Qiu K, Li K, Zeng T, Liao Y, Min J, Zhang N, Peng M, Kong W, Chen LL. Integrative Analyses of Genes Associated with Hashimoto’s Thyroiditis. J Immunol Res. 2021 Aug 28;2021:8263829. doi: 10.1155/2021/8263829. PMID: 34493981; PMCID: PMC8418929.

11 Liontiris MI, Mazokopakis EE. A concise review of Hashimoto thyroiditis (HT) and the importance of iodine, selenium, vitamin D and gluten on the autoimmunity and dietary management of HT patients.Points that need more investigation. Hell J Nucl Med. 2017 Jan-Apr;20(1):51-56. doi: 10.1967/s002449910507. Epub 2017 Mar 20. PMID: 28315909.

12 Guastamacchia E, Giagulli VA, Licchelli B, Triggiani V. Selenium and Iodine in Autoimmune Thyroiditis. Endocr Metab Immune Disord Drug Targets. 2015;15(4):288-92. doi: 10.2174/1871530315666150619094242. PMID: 26088475.

13 Kim D. The Role of Vitamin D in Thyroid Diseases. Int J Mol Sci. 2017 Sep 12;18(9):1949. doi: 10.3390/ijms18091949. PMID: 28895880; PMCID: PMC5618598.

14 Dahiya V, Vasudeva N, Sharma S, Kumar A. Role of Dietary Supplements in Thyroid Diseases. Endocr Metab Immune Disord Drug Targets. 2022;22(10):985-996. doi: 10.2174/1871530322666220419125131. PMID: 35440339.

15 Hu S, Rayman MP. Multiple Nutritional Factors and the Risk of Hashimoto’s Thyroiditis. Thyroid. 2017 May;27(5):597-610. doi: 10.1089/thy.2016.0635. Epub 2017 Apr 6. PMID: 28290237.

16 Knezevic J, Starchl C, Tmava Berisha A, Amrein K. Thyroid-Gut-Axis: How Does the Microbiota Influence Thyroid Function? Nutrients. 2020 Jun 12;12(6):1769. doi: 10.3390/nu12061769. PMID: 32545596; PMCID: PMC7353203.

17 Gaberšček S, Zaletel K. Thyroid physiology and autoimmunity in pregnancy and after delivery. Expert Rev Clin Immunol. 2011 Sep;7(5):697-706; quiz 707. doi: 10.1586/eci.11.42. PMID: 21895480.

What Causes Weight Gain

What Causes Weight Gain – How To Finally Lose Fat And Keep It Off

Let’s take a look at what causes weight gain, as lifestyle choices, underlying medical conditions, medications, chemicals, and hormones all play a role. Eating too much unhealthy food along with a sedentary lifestyle are the most common causes of weight gain. However, there is more to weight gain than just excess calorie consumption, as you will soon see.

What Causes Weight Gain – Consuming Excess Calories

The most common reason for weight gain is consuming more calories than the body needs. Americans consume an average of 3,682 calories per day, far more than the recommended daily caloric consumption.1 Weight gain occurs when one takes in more calories than they burn through normal daily activities and exercise. For people who are overweight or obese, reducing calorie intake helps promote weight loss. 

Eating a balanced diet that includes plenty of fruits, vegetables, grass-fed meat, and healthy fats like olive oil is the best way to ensure that you are getting the nutrients your body needs while also managing weight. Avoiding processed foods, refined carbohydrates, and added sugars can also help reduce caloric intake and lead to a healthier lifestyle.

What Causes Weight Gain - Consuming Excess Calories

What Causes Weight Gain – Sugar

Sugar is a major contributor to weight gain. It’s no secret that sugary foods and drinks can lead to an increase in overall calorie intake, leading to weight gain.2 Sugar-sweetened beverages are one of the biggest sources of added sugar in the modern diet. Research links regular consumption of these drinks with obesity and a range of other health issues such as diabetes disease and stroke.3 Cutting out sugary drinks is a great way to reduce your calorie intake and start losing weight.

Replacing sugary drinks with water or unsweetened beverages can also help you meet your daily nutrition needs more easily. Furthermore, avoiding processed foods that contain added sugars is essential for successful weight management. Sugar can be found in everything from breads and cereals to canned soups and salad dressings. Even seemingly healthy products like granola bars and yogurt can contain surprisingly high levels of added sugars. Reading nutrition labels is a great way to identify items that are loaded with added sugar so you can make better choices when it comes to your food shopping.

Read more about how toxic sugar is.

What Causes Weight Gain – HFCS

High Fructose Corn Syrup (HFCS) is a sugar substitute made from corn that has been linked to weight gain. Studies have shown that regular consumption of HFCS can lead to increased body fat and an increase in visceral fat, which is the type of fat that accumulates around organs and increases the risk for chronic diseases such as diabetes and heart disease.4

HFCS is found in many processed foods, including soda and sweetened beverages, cereal bars, and even some breads. When you consume high quantities of these products that contain HFCS, you are taking in a large amount of calories without being aware of it. Reducing your consumption of HFCS can help you to maintain a healthy weight and reduce your risk for chronic diseases.5

Aside from weight gain, the consumption of large amounts of HFCS has also been linked to other health concerns such as an increased risk of type 2 diabetes, high cholesterol, liver damage, and even certain types of cancer. It is important to be aware of the amount of HFCS you are consuming on a regular basis and to look for healthier alternatives whenever possible. When choosing processed foods, try to find those that do not contain HFCS or other types of added sugars. Eating a balanced diet and staying active will help maintain a healthy weight and reduce the risk of diseases associated with high consumption of sugar.6

What Causes Weight Gain - HFCS

What Causes Weight Gain – Artificial Sweeteners

Artificial sweeteners are a popular calorie-free alternative to sugar, but research suggests that they may actually contribute to weight gain.7 Studies have shown that consuming artificial sweeteners can lead to an increase in appetite and cravings for sweet and high-calorie foods.8

This could be due to the fact that artificial sweeteners disrupt the body’s natural ability to detect sweetness and regulate caloric intake. Additionally, research has found that artificial sweeteners might also alter gut bacteria in a way that increases cravings for sugary food and promotes fat accumulation.9 Consumption of sucralose has recently been linked with being a primary cause of Leaky Gut Syndrome.10

Read more about Leaky Gut Syndrome.

What Causes Weight Gain – Endocrine Disruptors

Endocrine disruptors play a role in weight gain. Endocrine disruptors are man-made chemicals found in everyday products such as plastic bottles, food packaging, cleaning supplies, and cosmetics. These chemicals can interfere with the body’s hormones, leading to health conditions such as diabetes, obesity, and reproductive issues.

Research has suggested that endocrine disruptors may affect weight gain by interfering with the hormone leptin and insulin. Endocrine-disrupting chemicals include phthalates, bisphenol A (BPA), and parabens.11

What Causes Weight Gain - Endocrine Disruptors

What Causes Weight Gain – BPA

BPA, or bisphenol A, is a chemical found in plastic products and has been linked to weight gain. The chemical leaches into food and beverages stored in many types of plastic containers and can disrupt hormones that regulate metabolism. Research shows that even low levels of BPA can have an adverse effect on metabolism, leading to weight gain.12

It is important to reduce or avoid exposure to BPA by minimizing plastic use and opting for glass or stainless steel containers when storing food or beverages. Additionally, look for products that are labeled “BPA-free” to ensure you are not exposing yourself to this potentially hazardous chemical. Making small changes in your daily habits can help you reduce your exposure to BPA and potentially prevent weight gain.

What Causes Weight Gain – Hypothyroidism

Hypothyroidism is a condition where the body does not produce enough thyroid hormone, which can lead to weight gain. Symptoms of hypothyroidism include fatigue, depression, constipation, dry skin, brittle hair and nails, and sensitivity to cold temperatures. People with hypothyroidism may find it difficult to lose weight, even when following a strict diet and exercise regimen.

The most common cause of hypothyroidism is Hashimoto’s disease, an autoimmune condition that causes the body to attack its own thyroid gland. Other potential causes of hypothyroidism include thyroiditis, a condition in which the body’s immune system mistakenly attacks its own thyroid gland, radiotherapy for cancer or other treatments that involve radiation, iodine deficiency, and medications such as lithium or interferon-alpha.13

Read more about hypothyroidism.

What Causes Weight Gain – Low Testosterone Levels

Low testosterone levels can cause weight gain, especially in the abdomen, and can lead to obesity. Low testosterone affects metabolism, how well the body stores fat, and how much energy one has. Men with low levels of testosterone often report feeling sluggish and lacking in energy, which leads to decreased activity and a decrease in muscle mass. This lack of physical activity leads to an increase in fat storage, especially around the abdomen. 

Low levels of testosterone can also increase your appetite, which can lead to overeating and weight gain. In addition, hormones that regulate metabolism are affected by low testosterone levels, so people with lower testosterone levels may find it harder to lose weight or keep it off.14

Read more about low testosterone levels.

What Causes Weight Gain - Low Testosterone Levels

What Causes Weight Gain – High Estrogen Levels

High estrogen levels can also contribute to an increase in body weight. Estrogen is a hormone found naturally in both men and women, but women tend to have higher levels of estrogen than men. When estrogen levels are too high, the body becomes more efficient at storing fat, leading to an increased risk for weight gain. Excess estrogen is also known to lead to water retention, which can add weight to the body. High estrogen levels can be caused by a number of different things such as certain medications, diet, and lifestyle choices.15

Read more about high estrogen levels.

What Causes Weight Gain – Polycystic Ovarian Syndrome

(PCOS) is an endocrine disorder that can cause weight gain. PCOS affects the hormones that regulate ovulation and menstruation, resulting in a number of symptoms related to hormone imbalance, such as excessive hair growth and acne. Irregular menstrual cycles or lack thereof are also common with PCOS. In addition to those physical signs, women with PCOS often have difficulty losing weight due to a combination of metabolic and hormonal changes. 

Insulin resistance, which is common with PCOS, can lead to increased levels of circulating insulin in the body that contribute to weight gain. Low-grade inflammation caused by PCOS may also contribute to difficulty with weight loss.16

What Causes Weight Gain – Anti-inflammatory Steroids

Weight gain can be caused by a number of factors, but one of the more common causes is the use of anti-inflammatory steroids. These medications are often prescribed to reduce inflammation in conditions such as arthritis and asthma, and while they can help relieve symptoms of these conditions, they can also lead to weight gain. This is because anti-inflammatory steroids often increase appetite, which can lead to increased caloric intake. Additionally, these medications can also cause the body to retain fluid, resulting in an increase in water weight.17

What Causes Weight Gain – Depression

Depression is a serious mental health disorder that can have far-reaching consequences. Not only can it lead to significant emotional distress, but it can also cause physical ailments and even weight gain. In many cases, depression may be related to changes in appetite or eating habits. People with depression often find themselves turning to food as a coping mechanism or way to deal with their emotional distress. Over time, this can lead to weight gain as they consume more calories than their body needs.

In addition to overeating, people with depression may also make poorer food choices. Depression can also affect the body’s metabolism, making it harder for the body to burn calories efficiently. This can further contribute to weight gain as well as other health issues like diabetes and heart disease.18 Additionally, typical antidepressant medications can also lead to weight gain.

What Causes Weight Gain - Depression

What Causes Weight Gain – Antidepressants

Weight gain is a common side effect of taking antidepressants. Most people will gain some weight when they start taking an antidepressant, especially if it’s a type of drug known as a tricyclic antidepressant. While the exact amount of weight gained varies from person to person, it’s not unusual to put on an extra 5 to 10 pounds over the course of a few months.

The weight gain is usually caused by an increase in appetite, which leads to more calorie consumption. Additionally, certain types of antidepressants can slow down your metabolism, meaning that the body doesn’t burn calories as quickly as it normally would. This combination of increased appetite and decreased metabolism can cause your weight to rise gradually over time.19

What Causes Weight Gain – Cushing’s Syndrome

Cushing’s Syndrome, also known as Hypercortisolism, is a hormonal disorder caused by excessive levels of the hormone cortisol in the body. It can be caused by either an overactive adrenal gland or taking artificial forms of cortisol through medications such as prednisone and hydrocortisone. 

Symptoms of Cushing’s Syndrome include rapid weight gain that is distributed evenly throughout the body, a round face with prominent cheeks and chin, thinning of the arms and legs, increased fat in the midsection and upper back, purple stretch marks on the skin, easy bruising, and fatigue. If left untreated, Cushing’s Syndrome can increase the risk of type 2 diabetes, heart disease, and high blood pressure.20

What Causes Weight Gain – Leptin Resistance

Leptin resistance is a major factor in weight gain. Leptin is a hormone that helps regulate hunger and energy levels. When the body becomes resistant to leptin, it no longer responds properly to signals from this hormone which can lead to increased appetite, overeating, and weight gain. Research suggests that insulin resistance is linked with leptin resistance as well.21

Read more about leptin resistance.

What Causes Weight Gain – Insulin Resistance

Insulin resistance is a major cause of weight gain. When the body becomes resistant to insulin, it can’t effectively use the glucose from carbohydrates in our diet for energy. As a result, the body stores more fat instead of using glucose as fuel, leading to weight gain. Besides affecting blood sugar levels, insulin resistance also increases appetite and slows down metabolism, making it harder for the body to burn calories. 

Therefore, individuals with insulin resistance are at a greater risk of gaining weight. To combat this, it is important to make dietary changes and get regular physical activity in order to improve insulin sensitivity and prevent unhealthy weight gain.22

Read more about insulin resistance.

What Causes Weight Gain - Insulin Resistance

What Causes Weight Gain – How To Finally Lose Fat And Keep It Off

When it comes to healthy weight loss, diet is one of the most important factors. Eating an ideal number of calories in whole, unprocessed foods is key to reaching most fat-loss goals. Foods such as grass-fed meat, nuts and seeds, organic fruits and vegetables, wild-caught fish, coconut oil, olive oil, and avocado are all excellent choices for those looking to lose fat.

Read more about my Cellular Healing Diet.

In addition to eating a nutritious diet, HIIT (high-intensity interval training) exercise can help you burn fat more quickly. HIIT involves short bursts of intense exercise followed by periods of rest or active recovery. This type of workout is great for burning large amounts of calories in a short amount of time.23

Finally, it is essential to correct any underlying hormone imbalances. Hormone imbalances cause the body to store fat more easily and decrease metabolism.

Read more about optimizing the hormones involved in fat loss.

References

1 Fierberg, E., & Gould, S. (2017). Here’s how the American diet has changed in the last 52 years. Business Insider. https://www.businessinsider.com/american-calorie-intake-last-52-years-diet-food-eating-increase-science-2017-6?op=1

2 Stanhope KL. Sugar consumption, metabolic disease and obesity: The state of the controversy. Crit Rev Clin Lab Sci. 2016;53(1):52-67. doi: 10.3109/10408363.2015.1084990. Epub 2015 Sep 17. PMID: 26376619; PMCID: PMC4822166.

3 StudyFinds.org. (2023, April 6). More than 6 teaspoons of sugar daily increases risk of 45 different health problems. Study Finds. https://studyfinds.org/6-teaspoons-of-sugar-health/

4 DiNicolantonio JJ, Mehta V, Onkaramurthy N, O’Keefe JH. Fructose-induced inflammation and increased cortisol: A new mechanism for how sugar induces visceral adiposity. Prog Cardiovasc Dis. 2018 May-Jun;61(1):3-9. doi: 10.1016/j.pcad.2017.12.001. Epub 2017 Dec 8. PMID: 29225114.

5 Stanhope KL, Bremer AA, Medici V, Nakajima K, Ito Y, Nakano T, Chen G, Fong TH, Lee V, Menorca RI, Keim NL, Havel PJ. Consumption of fructose and high fructose corn syrup increase postprandial triglycerides, LDL-cholesterol, and apolipoprotein-B in young men and women. J Clin Endocrinol Metab. 2011 Oct;96(10):E1596-605. doi: 10.1210/jc.2011-1251. Epub 2011 Aug 17. PMID: 21849529; PMCID: PMC3200248.

6 Ferder L, Ferder MD, Inserra F. The role of high-fructose corn syrup in metabolic syndrome and hypertension. Curr Hypertens Rep. 2010 Apr;12(2):105-12. doi: 10.1007/s11906-010-0097-3. PMID: 20424937.

7 Artificial Sweeteners and Leptin; Impaired Lipid Storage and Starvation | NIH Intramural Research Program. (2014). https://irp.nih.gov/catalyst/22/3/artificial-sweeteners-and-leptin-impaired-lipid-storage-and-starvation

8 Yang Q. Gain weight by “going diet?” Artificial sweeteners and the neurobiology of sugar cravings: Neuroscience 2010. Yale J Biol Med. 2010 Jun;83(2):101-8. PMID: 20589192; PMCID: PMC2892765.

9 Ruiz-Ojeda FJ, Plaza-Díaz J, Sáez-Lara MJ, Gil A. Effects of Sweeteners on the Gut Microbiota: A Review of Experimental Studies and Clinical Trials. Adv Nutr. 2019 Jan 1;10(suppl_1):S31-S48. doi: 10.1093/advances/nmy037. Erratum in: Adv Nutr. 2020 Mar 1;11(2):468. PMID: 30721958; PMCID: PMC6363527.

10 Méndez-García LA, Bueno-Hernández N, Cid-Soto MA, De León KL, Mendoza-Martínez VM, Espinosa-Flores AJ, Carrero-Aguirre M, Esquivel-Velázquez M, León-Hernández M, Viurcos-Sanabria R, Ruíz-Barranco A, Cota-Arce JM, Álvarez-Lee A, De León-Nava MA, Meléndez G, Escobedo G. Ten-Week Sucralose Consumption Induces Gut Dysbiosis and Altered Glucose and Insulin Levels in Healthy Young Adults. Microorganisms. 2022 Feb 14;10(2):434. doi: 10.3390/microorganisms10020434. PMID: 35208888; PMCID: PMC8880058.

11 Endocrine Disruptors. (2022.). National Institute of Environmental Health Sciences. https://www.niehs.nih.gov/health/topics/agents/endocrine/index.cfm

12 Neuroepic. (2022, June). BPA: Not A-gouti Thing for You –. https://neuroepic.mcdb.lsa.umich.edu/wp/14-bpa-not-a-gouti-thing-for-you/

13 Chaker L, Bianco AC, Jonklaas J, Peeters RP. Hypothyroidism. Lancet. 2017 Sep 23;390(10101):1550-1562. doi: 10.1016/S0140-6736(17)30703-1. Epub 2017 Mar 20. PMID: 28336049; PMCID: PMC6619426.

14 Mogri, M., Dhindsa, S., Quattrin, T., Ghanim, H., & Dandona, P. (2013). Testosterone concentrations in young pubertal and post-pubertal obese males. Clinical endocrinology, 78(4), 593–599. https://doi.org/10.1111/cen.12018

15 Grantham, J. P., & Henneberg, M. (2014). The Estrogen Hypothesis of Obesity. PLOS ONE, 9(6), e99776. https://doi.org/10.1371/journal.pone.0099776

16 Teede HJ, Joham AE, Paul E, Moran LJ, Loxton D, Jolley D, Lombard C. Longitudinal weight gain in women identified with polycystic ovary syndrome: results of an observational study in young women. Obesity (Silver Spring). 2013 Aug;21(8):1526-32. doi: 10.1002/oby.20213. Epub 2013 Jul 2. PMID: 23818329.

17 Tamez-Pérez HE, Quintanilla-Flores DL, Rodríguez-Gutiérrez R, González-González JG, Tamez-Peña AL. Steroid hyperglycemia: Prevalence, early detection and therapeutic recommendations: A narrative review. World J Diabetes. 2015 Jul 25;6(8):1073-81. doi: 10.4239/wjd.v6.i8.1073. PMID: 26240704; PMCID: PMC4515447.

18 Patsalos O, Keeler J, Schmidt U, Penninx BWJH, Young AH, Himmerich H. Diet, Obesity, and Depression: A Systematic Review. J Pers Med. 2021 Mar 3;11(3):176. doi: 10.3390/jpm11030176. PMID: 33802480; PMCID: PMC7999659.

19 Alonso-Pedrero L, Bes-Rastrollo M, Marti A. Effects of antidepressant and antipsychotic use on weight gain: A systematic review. Obes Rev. 2019 Dec;20(12):1680-1690. doi: 10.1111/obr.12934. Epub 2019 Sep 16. PMID: 31524318.

20 Nieman LK. Recent Updates on the Diagnosis and Management of Cushing’s Syndrome. Endocrinol Metab (Seoul). 2018 Jun;33(2):139-146. doi: 10.3803/EnM.2018.33.2.139. PMID: 29947171; PMCID: PMC6021313.

21 Pan H, Guo J, Su Z. Advances in understanding the interrelations between leptin resistance and obesity. Physiol Behav. 2014 May 10;130:157-69. doi: 10.1016/j.physbeh.2014.04.003. Epub 2014 Apr 12. PMID: 24726399.

22 Verkouter I, Noordam R, le Cessie S, van Dam RM, Lamb HJ, Rosendaal FR, van Heemst D, de Mutsert R. The Association between Adult Weight Gain and Insulin Resistance at Middle Age: Mediation by Visceral Fat and Liver Fat. J Clin Med. 2019 Sep 28;8(10):1559. doi: 10.3390/jcm8101559. PMID: 31569345; PMCID: PMC6832997.

23 Boutcher S. H. (2011). High-intensity intermittent exercise and fat loss. Journal of obesity, 2011, 868305. https://doi.org/10.1155/2011/868305

How To Achieve Ideal Health

How To Achieve Ideal Health – And Live A Life Worth Living

If you want to achieve ideal health, there are countless steps to take. Ideal health is a relative concept, as we will never achieve perfection. However, if we continue to improve while waking up healthier and happier every single day, we are on the right path. The journey to ideal health involves eating correctly, exercising, sleeping restfully, removing toxins from our environment and bodies, optimizing microbiome function, and maximizing ideal epigenetic expression.

How To Achieve Ideal Health – Diet

A high-fat, moderate protein, low-carb diet is the best way to achieve ideal health. This type of diet includes grass-fed meat, vegetables, fruits, nuts, and seeds, grass-fed dairy products like yogurt, butter, kefir, and cheese, and healthy fats like olive oil, coconut oil, and avocado oil. Eating foods in their natural state is important. Avoid processed and packaged items altogether.

If you are accustomed to eating the Standard American Diet, my Cellular Healing Diet will be hard at first, but if you stick with it, the health improvements you will experience will be nothing short of a miracle. You will feel more energized, have less inflammation, have better digestion and sleep, improved skin health, and have clearer mental focus.1

Read more about my Cellular Healing Diet.

How To Achieve Ideal Health - Diet

How To Achieve Ideal Health – Exercise

Getting regular exercise is also essential for achieving ideal health. Exercise helps to keep your body in good shape by strengthening muscles and improving flexibility, endurance, and balance. It can also help reduce stress levels, which is beneficial both physically and mentally. Try to focus on activities that you enjoy, such as walking, running, swimming, or yoga.

When it comes to exercise, I recommend a combination of strength training, high-intensity interval training (HIIT), and low-impact activities like walking. Strength training is important because it builds muscle and increases metabolism. HIIT also boosts metabolism and helps burn fat faster. Lastly, low-impact activities like walking are great for overall health, helping to reduce stress and improve mood.2

How To Achieve Ideal Health – Adequate Sleep

Make sure that you are getting enough rest each night. Most people require at least seven to eight hours of sleep per night in order to stay healthy and alert. Sleep is when the body repairs itself from the wear and tear of daily life and helps keep energy levels up throughout the day.

If you are having issues sleeping, focus on improving sleep hygiene. This includes creating a relaxing bedtime routine, avoiding caffeine late in the day, and limiting screen time before bed. Morning exercise can also help improve nighttime sleep, as it tires the body out and helps regulate the sleep cycle. Additionally, make sure that the bedroom is comfortable, dark, and an ideal temperature of about 65°F to create an environment conducive to sleep.3 4

How To Achieve Ideal Health - Adequate Sleep

How To Achieve Ideal Health – Identifying And Removing Toxins From Your Life

Toxins are everywhere, and they can affect your health in various ways. To achieve ideal health, it’s important to identify and remove as many toxins as possible from your life. This may involve making lifestyle changes, such as quitting smoking or eating a healthier diet. 

You’ll also want to look for natural alternatives that reduce toxin exposure, such as using natural cleaning products or avoiding chemical-laden beauty and personal care items. Finally, regular detoxing can help your body get rid of toxins that have built up over time.

Read more about common toxins that we should stay away from.

How To Achieve Ideal Health – Removing Heavy Metals From The Body With DMSA Or DMPS

Heavy metals can accumulate in the body and cause a variety of health problems. To reduce the amount of heavy metals in your body, you may choose to use either DMSA or DMPS chelation therapies.

DMSA (dimercapto-succinic acid) is an oral medication that binds to toxic metals such as lead, mercury, arsenic, and cadmium and helps to remove them from the body. It is effective at removing lead from the brain, kidneys, blood, liver, and bone. DMSA chelation can be used as an adjunct therapy for mercury poisoning or in cases of acute heavy metal toxicity.

DMPS (dimercapto-propane sulfonate) is also an oral medication that binds to heavy metals such as lead, mercury, arsenic, cadmium, and cobalt. It is effective at removing toxic metals from the body’s tissues and organs. DMPS can also help to restore normal function of the liver, kidney, and other organs.

When used correctly, DMSA and DMPS can be effective tools in achieving optimal health and wellness by removing harmful heavy metals from the body.5 6

Read more about chelation therapy.

How To Achieve Ideal Health – Avoid Toxic Mold

Mold can be extremely toxic to your health. Mold spores are microscopic and can travel through the air, potentially exposing you to many potential toxins or allergens. Exposure to mold can cause severe allergic reactions, respiratory conditions, skin rashes, and other physical symptoms. It is important to recognize the signs of a mold infestation in your home as mold can quickly become a hazard to your health.

If you suspect mold in your home, it is important to act quickly and take steps to rid your home of the toxic spores. The first step is to identify any areas where moisture has collected, as mold can easily grow in damp or humid environments. Pay close attention to areas such as bathrooms, basements, kitchens, laundry rooms, and attics. If you do find mold in your home, it is important to clean the affected area thoroughly using chlorine bleach or a special mold cleaner.

It is also important to take steps to prevent mold from growing in your home in the future. Make sure that areas of high humidity are well-ventilated, and use dehumidifiers if necessary. By taking the necessary steps to reduce mold levels in your home, you can help protect yourself from potential health risks linked to exposure to toxic mold.7 8

Read more about the effects of toxic mold.

How To Achieve Ideal Health - Avoid Toxic Mold

How To Achieve Ideal Health – Optimizing Microbiome Function

The next step in achieving ideal health is to optimize microbiome function. The microbiome is made up of the billions of microorganisms that inhabit our bodies and have an important role in maintaining metabolic, gut, and immune health. A balanced microbiome can help reduce inflammation, improve digestion, boost immunity, and regulate hormones.9

To optimize your microbiome you should focus on eating a diet that is high in prebiotics and probiotics. Eating plenty of fruits and vegetables will provide your body with the necessary fiber it needs to feed the beneficial bacteria in your gut. You should also focus on getting sufficient amounts of omega-3 fatty acids from sources like fish or walnuts as these have been shown to improve gut health.10 11 12

Fermented foods are an important part of a healthy diet, as they contain beneficial bacteria and yeasts that can help to maintain the balance of microbes in your body. Eating fermented foods regularly helps to keep your gut microbiome rich and balanced, which is vital for optimal health. This means that by adding fermented foods such as sauerkraut, kimchi, and kefir to your diet, you can help support and improve the health of the gut microbiome.13

In addition to a balanced microbiome, fermented foods are also a great source of essential vitamins and minerals. By consuming fermented vegetables, you’ll be getting an array of beneficial micronutrients that will help nourish your body. The bacteria in fermented foods can also help to break down and absorb nutrients, making them more bioavailable for your body to use.

Fermented foods can also help improve digestion and promote regularity. The beneficial bacteria in these foods aid in the breakdown of food particles, helping you to better digest your meals. This improved digestion helps ensure that your body gets all the nutrients it needs from the foods you eat.

Finally, fermented foods can also help to reduce inflammation and its associated symptoms. The bacteria in these foods produce lactic acid, which helps to reduce inflammation in your gut, leading to improved overall health and well-being.14

Read more about the microbiome.

How To Achieve Ideal Health – Optimizing Epigenetic Expression With Methyl Donor Supplements

Methyl donors are an essential part of the nutrition we need to live healthy lives. They help our bodies process and utilize nutrients like proteins, carbohydrates, and fats so that we can have optimal energy levels. Methyl donors also play a role in gene expression, which is when genes turn on and off. By supplementing with methyl donor compounds, we can optimize our epigenetic expression. This means that we have the ability to influence how our genes express themselves, allowing us to achieve ideal health.15

Methyl donors are found in a variety of dietary sources including fish, nuts, seeds, and green leafy vegetables. They can also be added to many types of nutritional supplements such as multivitamins. When supplementing with methyl donor compounds, it is important to ensure that all essential nutrients are included in the formulation. Additionally, the dosage should be based on an individual’s needs and biochemistry.

Some of the most popular methyl donor supplements include folate, methionine, choline, SAMe (S-adenosylmethionine), betaine trimethylglycine (TMG), and N-acetylcysteine (NAC). These compounds are involved in a wide range of biological processes including energy production, detoxification, inflammation, neurotransmitter synthesis, and metabolic regulation. Supplementation with these compounds can help support optimal epigenetic expression so that we can achieve ideal health.16 17 18

Read more about epigenetic methylation.

Optimizing Epigenetic Expression With Methyl Donor Supplements

How To Achieve Ideal Health – Relaxation

Relaxation is an important part of achieving ideal health. It helps to reduce stress, improve mood, and even boost immunity. Relaxation comes in many forms, such as deep breathing exercises, yoga poses, meditation, or simply taking a few moments to sit quietly and clear your mind. 

Stress can have a negative effect on your mental and physical health, so it’s important to take time for yourself each day. Whether this means meditating, reading a book or simply taking a hot bath, find activities that help you reduce stress and enjoy life.

Taking time to relax also provides much-needed physical rest for the body after periods of intense activity. Regularly taking time to relax can help you achieve and maintain good physical, mental, and emotional health. To get the most benefit out of relaxation, it is important to make it part of your daily routine. 

Find a few minutes here and there throughout the day or dedicate an hour each week to do something relaxing that helps you clear your head and recharge. You can also try incorporating relaxation techniques into your daily tasks, such as deep breathing when feeling overwhelmed or taking a few moments to meditate before tackling something stressful. With a little practice and dedication, you are well on your way to achieving ideal health through relaxation.

How To Achieve Ideal Health – Spirituality

Spirituality is often overlooked when it comes to health and wellness. Yet, research has demonstrated that spiritual practices like mindfulness meditation can have profound effects on physical health. Studies suggest that incorporating spiritual practice into your daily life can reduce stress, improve sleep quality, boost mood, and even prevent chronic diseases.19

When people talk about spirituality in relation to health and wellness, they are usually referring to practices that promote a sense of connection and peace. This could include meditation, prayer, yoga, or Tai Chi. All of these activities can help you focus on the present moment and find inner calmness. They also provide opportunities for reflection and personal growth.

How To Achieve Ideal Health - Spirituality

How To Achieve Ideal Health – Personal Improvement

Once you have identified your current health issues, the next step is to create a personal improvement plan. This should include setting realistic goals and action steps that will help you reach those goals. For example, if one of your goals is to exercise more, set aside time each day or week specifically for physical activity and try to stick to it as much as possible. Make sure to monitor your progress so that you can adjust your plan as needed.

How To Achieve Ideal Health – And Live A Life Worth Living

Now that you know how to achieve ideal health, adopt healthy eating habits, engage in regular physical activity, get enough restful sleep, eliminate toxins from your lifestyle and body, restore proper microbiome function, and optimize epigenetic expression. By doing so, we can ensure our bodies are functioning at their best and maximize our chances of an enjoyable, long, and healthy life.

Read more about how to reduce chronic inflammation.

References

1 Ricordi C, Garcia-Contreras M, Farnetti S. Diet and Inflammation: Possible Effects on Immunity, Chronic Diseases, and Life Span. J Am Coll Nutr. 2015;34 Suppl 1:10-3. doi: 10.1080/07315724.2015.1080101. PMID: 26400428.

2 Boutcher S. H. (2011). High-intensity intermittent exercise and fat loss. Journal of obesity, 2011, 868305. https://doi.org/10.1155/2011/868305

3 Irish LA, Kline CE, Gunn HE, Buysse DJ, Hall MH. The role of sleep hygiene in promoting public health: A review of empirical evidence. Sleep Med Rev. 2015 Aug;22:23-36. doi: 10.1016/j.smrv.2014.10.001. Epub 2014 Oct 16. PMID: 25454674; PMCID: PMC4400203.

4 Pacheco, D., & Pacheco, D. (2023). Best temperature for sleep. Sleep Foundation. https://www.sleepfoundation.org/bedroom-environment/best-temperature-for-sleep

5 Miller AL. Dimercaptosuccinic acid (DMSA), a non-toxic, water-soluble treatment for heavy metal toxicity. Altern Med Rev. 1998 Jun;3(3):199-207. PMID: 9630737.

6 Sears ME. Chelation: harnessing and enhancing heavy metal detoxification–a review. ScientificWorldJournal. 2013 Apr 18;2013:219840. doi: 10.1155/2013/219840. PMID: 23690738; PMCID: PMC3654245. 

7 Tessier, L. (2020, February 10). Endocrine Impacts of Mycotoxins. Naturopathic Doctor News and Review. https://ndnr.com/endocrinology/endocrine-impacts-of-mycotoxins/

8 Mold allergy – Symptoms and causes. (2021, June 21). Mayo Clinic. https://www.mayoclinic.org/diseases-conditions/mold-allergy/symptoms-causes/syc-20351519

9 Thursby E, Juge N. Introduction to the human gut microbiota. Biochem J. 2017 May 16;474(11):1823-1836. doi: 10.1042/BCJ20160510. PMID: 28512250; PMCID: PMC5433529.

10 Davani-Davari D, Negahdaripour M, Karimzadeh I, Seifan M, Mohkam M, Masoumi SJ, Berenjian A, Ghasemi Y. Prebiotics: Definition, Types, Sources, Mechanisms, and Clinical Applications. Foods. 2019 Mar 9;8(3):92. doi: 10.3390/foods8030092. PMID: 30857316; PMCID: PMC6463098.

11 Wang X, Zhang P, Zhang X. Probiotics Regulate Gut Microbiota: An Effective Method to Improve Immunity. Molecules. 2021 Oct 8;26(19):6076. doi: 10.3390/molecules26196076. PMID: 34641619; PMCID: PMC8512487.

12 Costantini L, Molinari R, Farinon B, Merendino N. Impact of Omega-3 Fatty Acids on the Gut Microbiota. Int J Mol Sci. 2017 Dec 7;18(12):2645. doi: 10.3390/ijms18122645. PMID: 29215589; PMCID: PMC5751248.

13 Leeuwendaal NK, Stanton C, O’Toole PW, Beresford TP. Fermented Foods, Health and the Gut Microbiome. Nutrients. 2022 Apr 6;14(7):1527. doi: 10.3390/nu14071527. PMID: 35406140; PMCID: PMC9003261.

14 Şanlier N, Gökcen BB, Sezgin AC. Health benefits of fermented foods. Crit Rev Food Sci Nutr. 2019;59(3):506-527. doi: 10.1080/10408398.2017.1383355. Epub 2017 Oct 20. PMID: 28945458.

15 Mahmoud AM, Ali MM. Methyl Donor Micronutrients that Modify DNA Methylation and Cancer Outcome. Nutrients. 2019 Mar 13;11(3):608. doi: 10.3390/nu11030608. PMID: 30871166; PMCID: PMC6471069.

16 Kiss E, Hajdu A, Forika G, Dank M, Krenacs T, Nemeth Z. The Effect of Dietary Methyl-Donor Intake and Other Lifestyle Factors on Cancer Patients in Hungary. Cancers (Basel). 2022 Sep 13;14(18):4432. doi: 10.3390/cancers14184432. PMID: 36139592; PMCID: PMC9496722.

17 Taylor, Rachael & Smith, Roger & Collins, Clare & Mossman, David & Wong, Michelle & Chan, Eng-Cheng & Evans, Tiffany-Jane & Attia, John & Smith, Tenele & Butler, Trent & Hure, A.. (2018). Methyl-Donor and Cofactor Nutrient Intakes in the First 2–3 Years and Global DNA Methylation at Age 4: A Prospective Cohort Study. Nutrients. 10. 273. 10.3390/nu10030273.

18 Vaccaro JA, Naser SA. The Role of Methyl Donors of the Methionine Cycle in Gastrointestinal Infection and Inflammation. Healthcare (Basel). 2021 Dec 29;10(1):61. doi: 10.3390/healthcare10010061. PMID: 35052225; PMCID: PMC8775811.

19 Lucchetti G, Koenig HG, Lucchetti ALG. Spirituality, religiousness, and mental health: A review of the current scientific evidence. World J Clin Cases. 2021 Sep 16;9(26):7620-7631. doi: 10.12998/wjcc.v9.i26.7620. PMID: 34621814; PMCID: PMC8462234.

What Causes Myositis

What Causes Myositis And Can It Be Prevented?

Exactly what causes myositis is unknown, but research suggests that it is caused by a combination of factors. These include genetic predisposition, environmental triggers such as infection or exposure to certain medications or chemicals, and other autoimmune diseases. A person’s risk for developing myositis can also increase if they have an existing condition that weakens the immune system. Some research suggests that myositis may be caused by a virus or bacteria, but it is still not certain what role these pathogens play in causing myositis.

It is important to note that there is no single cause of myositis and researchers continue to investigate possible causes. Knowing the cause of a person’s myositis can help in determining the best treatment options for managing their condition. Additionally, further research into understanding the causes of myositis may eventually lead to better treatment and even prevention of this debilitating disease.

Autoimmune Conditions That Cause Myositis

Myositis is an inflammatory condition that affects the muscles. It can be caused by a variety of autoimmune diseases, including polymyositis, dermatomyositis, and inclusion body myositis.

Polymyositis is an autoimmune disorder in which the body’s immune system attacks its own muscles, causing inflammation and weakness. It can affect muscle groups all over the body, including those in the arms, legs, and face. Symptoms of polymyositis may include muscle weakness, muscle pain or tenderness, difficulty swallowing, and fatigue.

Dermatomyositis is another autoimmune disorder that can cause myositis. It is characterized by a skin rash as well as inflammation of the muscles. The most common symptom of dermatomyositis is a purplish-red, scaly rash on the face, chest, and back. Other symptoms may include muscle weakness, difficulty climbing stairs, and swallowing difficulties.

Inclusion body myositis (IBM) is an autoimmune disorder that causes progressive muscle weakness, primarily in the hands and feet. It can also cause difficulty swallowing and muscle pain. IBM is more common in people over the age of 50.

Myositis can also be caused by other autoimmune diseases, such as lupus, rheumatoid arthritis, and scleroderma. These diseases cause inflammation all over the body, including in the muscles. They may also cause fatigue, joint pain and swelling, skin rashes, and other symptoms.1

What Causes Myositis

Common Autoimmune Conditions

There are over 23 million people in the US who are affected by autoimmune diseases. Known autoimmune conditions include Rheumatoid Arthritis, Lupus, Multiple Sclerosis, and Type 1 Diabetes.

Rheumatoid Arthritis is a condition that causes chronic inflammation in the joints and other areas of the body, resulting in pain, fatigue, and stiffness.

Read more about Rheumatoid Arthritis.

The condition called Systemic Lupus Erythematosus is an autoimmune disease that can cause inflammation in any part of the body. It is also capable of harming organs like the heart, lungs, skin, and kidneys.

Read more about Lupus.

The neurological disorder known as Multiple Sclerosis gradually affects the brain and spinal cord. Its symptoms may include vision problems, muscle weakness, sensations changes, and fatigue.

Read more about Multiple Sclerosis.

Type 1 Diabetes is a medical condition that occurs when the immune system destroys insulin-producing cells in the pancreas. To maintain healthy blood sugar levels, constant management is required.

Read more about Type 1 Diabetes.

What Causes Myositis – Infections

Infections are one of the most common causes of myositis. Bacterial, viral, and fungal infections can cause inflammation in the muscles, leading to damage and pain. Viral infections such as influenza, human parvovirus B19, HIV/AIDS, Epstein Barr virus (EBV), cytomegalovirus (CMV), and enteroviruses, can cause inflammation and lead to myositis. Bacterial infections such as staphylococcus aureus and group A streptococcus may also be the culprits. In rare cases, fungal infections have been linked to myositis.2

Parasitic infections are another cause of myositis. These infections can be caused by a variety of different parasites, such as roundworms, tapeworms, and hookworms. Some types of parasites, such as those found in contaminated food or water, can cause infection when they enter the body through the skin or digestive system.3

What Causes Myositis – Drugs

Certain drugs are known to cause myositis. Many drugs, both prescription and over-the-counter (OTC), can cause an inflammatory response in the muscles. This can manifest as myositis or other related conditions such as dermatomyositis, polymyositis, and inclusion body myositis.

Common medications associated with myositis include hydroxychloroquine (Plaquenil), statins, simvastatin (Zocor), atorvastatin (Lipitor), lovastatin (Mevacor), and fluoroquinolones. Other drugs such as antiretrovirals, anticonvulsants, benzodiazepines, cancer drugs, and some antibiotics can also trigger myositis.4 5 6

What Causes Myositis – Muscle Injury

Muscle injury is one of the most common causes of myositis. This can be due to a traumatic event such as an accident or overexertion, or it can develop gradually over time through poor posture and ergonomics, repetitive motions, and other activities that increase strain on the muscles. If left untreated, muscle injury can cause inflammation in the affected muscles, leading to myositis. Treatment for muscle injury-related myositis typically involves rest, physical therapy, and medications to reduce inflammation and pain. If the injury is severe enough, surgery may be necessary to repair the affected muscles.7

What Causes Myositis - Muscle Injury

Myositis And Interstitial Lung Disease

Myositis and interstitial lung disease (ILD) are two different medical conditions that are often linked together. ILD is a broad term that describes any type of inflammation or scarring of the lungs. Both of these conditions can lead to a variety of respiratory symptoms, and may even cause breathing difficulties.

Research has shown that people with myositis are at an elevated risk for developing ILD or other lung diseases. This is because myositis can cause inflammation in other areas of the body, including the lungs. Additionally, certain medications used to treat myositis can also increase the risk of developing ILD.8

What Causes Myositis – Genetics

Myositis can be caused by certain inherited genetic mutations as well as environmental factors. It has been found that people with certain family histories are more likely to develop the condition, suggesting a genetic component. Studies have also shown an increased risk of myositis in individuals who have particular HLA-DRB1 gene variants.9

What Causes Myositis – Environmental Factors

Some environmental factors that are responsible for causing myositis include exposure to certain toxins, such as those found in industrial waste, occupational or residential pesticides, and solvents.

What Causes Myositis – Organophosphorus Pesticides

Organophosphorus Pesticides (OPs) are widely used in agriculture and are known cause myositis. Long-term exposure to OPs can lead to muscle weakness, fatigue, and cramps. OPs cause muscle damage and inflammation when ingested or inhaled. Exposure to these products results in an inflammatory response in the body, which leads to muscle weakness and stiffness.10

Additionally, certain pesticides may contain heavy metals that can act as neurotoxins, further contributing to muscular problems such as myositis. People who work in agricultural fields or with products that contain pesticides may be especially at risk of developing this condition. To reduce the risk, people should avoid unnecessary contact with these products and wear protective clothing when necessary.

What Causes Myositis – Air Pollution

Air pollution is composed of a variety of particles, such as ozone, nitrogen dioxide, and particulate matter. These substances can irritate the airways and cause inflammation throughout the body. This can lead to an increased risk for autoimmune diseases, like myositis. Research has shown that people living in urban areas with higher levels of air pollution are more likely to develop myositis than those living in rural areas.11

What Causes Myositis – Prenatal Exposure To Tobacco Smoke

Research suggests that children born to mothers who smoked during pregnancy have an increased risk of developing myositis. It is believed that prenatal exposure to tobacco can cause the body’s immune system to be weakened, resulting in a higher likelihood of developing an autoimmune disorder like myositis.12

What Causes Myositis - Prenatal Exposure To Tobacco Smoke

What Causes Myositis – Vitamin D Deficiency

Vitamin D deficiency is one of several potential causes of myositis. Vitamin D helps to maintain strong muscles as it helps the body absorb calcium, and when the levels are too low, muscle weakness can develop. People who have a vitamin D deficiency due to diet or lack of sun exposure may be more prone to developing myositis.

Low levels of vitamin D have been linked to several types of autoimmune illnesses including myositis. Vitamin D can reduce inflammation in the body which has a direct impact on muscle tissue. Without enough vitamin D, it can be difficult for the body to repair damaged muscle fibers, leading to the development of myositis.13 

In addition to dietary changes and taking supplements, increasing sun exposure is the best way to increase Vitamin D levels in the body.

Read more about how crucial vitamin D is for those suffering from autoimmune conditions.

What Causes Myositis And Can It Be Prevented?

Exactly what causes myositis includes genetic factors, prenatal factors, and environmental factors. As with any other autoimmune condition, improving lifestyle choices as well as ensuring optimal vitamin D intake reduces the risk of developing these conditions.

Read more about what causes autoimmune conditions.

References

1 Hoffman, M., MD. (2011, February 9). Myositis. WebMD. https://www.webmd.com/a-to-z-guides/myositis-symptoms-treatments-prognosis

2 Adams EM, Gudmundsson S, Yocum DE, Haselby RC, Craig WA, Sundstrom WR. Streptococcal myositis. Arch Intern Med. 1985 Jun;145(6):1020-3. PMID: 3890787.

3 El-Beshbishi SN, Ahmed NN, Mostafa SH, El-Ganainy GA. Parasitic infections and myositis. Parasitol Res. 2012 Jan;110(1):1-18. doi: 10.1007/s00436-011-2609-8. Epub 2011 Sep 1. PMID: 21881948.

4 Klopstock T. Drug-induced myopathies. Curr Opin Neurol. 2008 Oct;21(5):590-5. doi: 10.1097/WCO.0b013e32830e2774. PMID: 18769254.

5 Doyno C, Sobieraj DM, Baker WL. Toxicity of chloroquine and hydroxychloroquine following therapeutic use or overdose. Clin Toxicol (Phila). 2021 Jan;59(1):12-23. doi: 10.1080/15563650.2020.1817479. Epub 2020 Sep 22. PMID: 32960100.

6 Tomaszewski M, Stępień KM, Tomaszewska J, Czuczwar SJ. Statin-induced myopathies. Pharmacol Rep. 2011;63(4):859-66. doi: 10.1016/s1734-1140(11)70601-6. PMID: 22001973.

7 Beiner JM, Jokl P. Muscle contusion injury and myositis ossificans traumatica. Clin Orthop Relat Res. 2002 Oct;(403 Suppl):S110-9. doi: 10.1097/00003086-200210001-00013. PMID: 12394459.

8 Hallowell RW, Paik JJ. Myositis-associated interstitial lung disease: a comprehensive approach to diagnosis and management. Clin Exp Rheumatol. 2022 Feb;40(2):373-383. doi: 10.55563/clinexprheumatol/brvl1v. Epub 2021 Mar 25. PMID: 33769263; PMCID: PMC8855729.

9 Lamb JA. The Genetics of Autoimmune Myositis. Front Immunol. 2022 May 26;13:886290. doi: 10.3389/fimmu.2022.886290. PMID: 35693792; PMCID: PMC9178267.

10 Karalliedde L, Baker D, Marrs TC. Organophosphate-induced intermediate syndrome: aetiology and relationships with myopathy. Toxicol Rev. 2006;25(1):1-14. doi: 10.2165/00139709-200625010-00001. PMID: 16856766.

11 Zhao N, Smargiassi A, Chen H, Widdifield J, Bernatsky S. Systemic autoimmune rheumatic diseases and multiple industrial air pollutant emissions: A large general population Canadian cohort analysis. Environ Int. 2023 Apr;174:107920. doi: 10.1016/j.envint.2023.107920. Epub 2023 Apr 8. PMID: 37068387.

12 Orione MA, Silva CA, Sallum AM, Campos LM, Omori CH, Braga AL, Farhat SC. Risk factors for juvenile dermatomyositis: exposure to tobacco and air pollutants during pregnancy. Arthritis Care Res (Hoboken). 2014 Oct;66(10):1571-5. doi: 10.1002/acr.22358. PMID: 24757124.

13 Glueck CJ, Abuchaibe C, Wang P. Symptomatic myositis-myalgia in hypercholesterolemic statin-treated patients with concurrent vitamin D deficiency leading to statin intolerance may reflect a reversible interaction between vitamin D deficiency and statins on skeletal muscle. Med Hypotheses. 2011 Oct;77(4):658-61. doi: 10.1016/j.mehy.2011.07.007. Epub 2011 Jul 29. PMID: 21802861.

What Causes Parkinson’s Disease

What Causes Parkinson’s Disease And Can It Be Prevented?

Exactly what causes Parkinson’s disease (PD) is still not known, but research suggests that it is caused by a combination of genetic and environmental factors. People with certain genetic mutations are at higher risk for developing the disease, however, the vast majority of people with Parkinson’s have no known family history of the disease. It may also be linked to exposure to toxins, such as herbicides and pesticides.

Certain changes in the brain contribute to Parkinson’s disease. It is believed that several years before any physical symptoms appear, chemical imbalances occur in the brain, leading to a gradual loss of nerve cells, specifically, neurons, that produce dopamine, the neurotransmitter responsible for controlling movement and coordination. 

As dopamine levels decline, symptoms of Parkinson’s begin to appear. Symptoms of Parkinson’s can include tremors, rigid muscles, slow movements, impaired balance and coordination, and difficulty speaking or swallowing.1

Parkinson’s Disease Is An Autoimmune Disease

New evidence indicates that Parkinson’s is an autoimmune disorder, meaning the body’s own immune system attacks and destroys the healthy nerve cells in the brain.2 As with other autoimmune conditions, a combination of factors is responsible for triggering these conditions, including genetic predisposition, environmental exposures, and microbiome dysbiosis.3

What Causes Parkinson's Disease

Autoimmune diseases affect more than 23 million people in the United States alone, and while there are many known autoimmune conditions, some of the most common ones include Rheumatoid Arthritis, Lupus, Multiple Sclerosis, Type 1 Diabetes, Celiac Disease, Inflammatory Bowel Disease, Psoriasis, Graves’ Disease, and Hashimoto’s Thyroiditis.

Rheumatoid Arthritis is a chronic inflammatory disorder that affects the joints and other parts of the body, causing pain, fatigue, and stiffness.

Read more about Rheumatoid Arthritis.

Systemic Lupus Erythematosus is an autoimmune disease that can affect any part of the body and cause inflammation. It is also known to damage organs like the kidneys, heart, lungs, and skin.

Read more about Lupus.

Multiple Sclerosis is a progressive neurological disorder that affects the brain and spinal cord. Symptoms include vision problems, muscle weakness, fatigue, and changes in sensation.

Read more about Multiple Sclerosis.

Type 1 Diabetes is a chronic condition that occurs when the immune system attacks and destroys insulin-producing cells in the pancreas. It requires ongoing management to keep blood sugar levels in check.

Read more about Type 1 Diabetes.

Celiac Disease is an inflammatory disorder that is triggered by gluten consumption and affects the digestive system, causing pain and problems with absorption of nutrients.

Read more about Celiac Disease.

Inflammatory Bowel Disease is a group of chronic disorders that cause inflammation in the digestive tract. They can cause abdominal pain, cramping, diarrhea, and fatigue.

Read more about Inflammatory Bowel Disease.

Psoriasis is a skin disorder that is characterized by red, scaly patches of skin that can be itchy and painful. It often appears on the elbows, knees, scalp, lower back, and genitals.

Read more about Psoriasis.

Graves’ Disease is an autoimmune disorder that affects the thyroid gland, causing an overactive thyroid and symptoms like weight loss, fatigue, muscle weakness, and tremors.

Read more about Graves’ Disease.

Hashimoto’s Thyroiditis is another thyroid disorder caused by the immune system attacking the gland. It causes an underactive thyroid and can lead to fatigue, weight gain, and depression.

Read more about Hashimoto’s Thyroiditis.

What Causes Parkinson’s Disease – Genetics

Genetics is one factor behind Parkinson’s disease. Multiple studies have identified specific gene variants that are associated with an increased risk of developing PD. People are more likely to develop PD if they have family members who suffer from the condition.

Recent research has uncovered a strong genetic link between Parkinson’s disease and other autoimmune diseases. The connection is in the form of genetic mutations, which increase an individual’s risk of developing both conditions. Some specific genes that may be linked to both Parkinson’s and other autoimmune conditions include MAPT, LRRK2, GAK, and HLA-DRB5.4

Parkinson’s Disease – Microglia And Neuroinflammation

Neuroinflammation plays an important role in the progression of Parkinson’s Disease. Microglia, the resident immune cells in the central nervous system, are activated in response to changes in the brain environment. Their activation leads to the release of a variety of pro-inflammatory molecules including nitric oxide, cytokines, and chemokines. This leads to a cascade of events resulting in the accumulation of potentially neurotoxic metabolites, and further inflammation that contributes to the progression of PD.5

Parkinson's Disease - Microglia And Neuroinflammation

What Causes Parkinson’s Disease – T Cells

One of the most interesting areas in the study of Parkinson’s Disease is the potential involvement of T cells. T cells are a type of white blood cell that has been found to play an important role in the body’s immune response to illness and infection, but they also appear to be involved in the development and progression of Parkinson’s Disease. 

Studies have found that T cells may be involved in the body’s inflammatory response to certain environmental triggers, such as exposure to toxins or other substances. This suggests that if these triggers can be avoided or otherwise managed, it may help reduce the risk of developing Parkinson’s Disease. 

Additionally, research has also found that some genetic mutations associated with Parkinson’s Disease can affect T cell function and lead to a more severe form of the disease. Further research is needed to better understand the role T cells may play in the development and progression of Parkinson’s Disease.6

What Causes Parkinson’s Disease – Autoantibodies

Autoantibodies are antibodies directed against the body’s own proteins. In Parkinson’s disease, autoantibodies to certain proteins, including alpha-synuclein and dopamine receptors, are present. It is unclear whether these autoantibodies are a cause or consequence of Parkinson’s. However, their presence may explain why certain individuals are more susceptible to developing the disease. In addition, some researchers believe that autoantibodies could be a potential target for Parkinson’s treatment.7

What Causes Parkinson’s Disease – Environmental Factors

Environmental factors have been linked to Parkinson’s Disease. Exposure to toxins, such as pesticides and herbicides, may increase the risk of developing PD. Additionally, head trauma has been associated with an increased risk of developing this condition.

What Causes Parkinson’s Disease – Pesticides And Herbicides

Certain environmental factors such as exposure to pesticides, herbicides, and other toxins can increase the risk of developing Parkinson’s Disease. Studies have found a link between long-term exposure to pesticide use in farm workers and people with Parkinson’s disease.8 9

What Causes Parkinson's Disease - Pesticides And Herbicides

What Causes Parkinson’s Disease – Mercury And Arsenic

Mercury exposure has been linked to an increased risk of developing Parkinson’s disease. This is because mercury accumulates in the brain and damages neurons, which can lead to abnormal electrical signals in the brain that cause Parkinson’s symptoms. Furthermore, studies have found that people with higher levels of mercury in their bodies were more likely to develop Parkinson’s than those without it.

Long-term exposure to arsenic can lead to an accumulation of the element in the body, which can damage certain areas of the brain responsible for motor control. This could lead to tremors and other symptoms associated with Parkinson’s. People exposed to high levels of arsenic through drinking water or occupational exposure have been found to be at a higher risk for developing Parkinson’s disease.10 11

What Causes Parkinson’s Disease – Microbiome Dysfunction

Recent research has revealed that an imbalance in the gut microbiome is a contributing factor to Parkinson’s disease. Specifically, studies have found that individuals with Parkinson’s have fewer beneficial bacteria and more pathogenic bacteria in their gastrointestinal tract compared to people without the disorder. Furthermore, researchers have identified particular bacterial species associated with Parkinson’s disease, including several strains of Streptococcus, Clostridium, and Enterococcus.

This microbiome imbalance contributes to inflammation in the body, which may lead to oxidative stress, a state in which toxic molecules are created that can damage cells throughout the body. This damage can eventually cause cell death or malfunction and increase an individual’s risk for Parkinson’s. Additionally, it has been suggested that some of the toxins released by certain types of bacteria may directly affect dopamine-producing neurons in the brain, further increasing an individual’s risk for Parkinson’s.12

What Causes Parkinson’s Disease – Low Vitamin D Levels

Low vitamin D levels have been linked to Parkinson’s disease, and treating low vitamin D levels may help to manage the symptoms of this condition. This is why it is important to get adequate exposure to the sun and consume foods that are high in vitamin D such as salmon, tuna, fortified milk, eggs, and mushrooms.13

Read more about the link between autoimmune conditions and low vitamin D levels.

What Causes Parkinson’s Disease – Vitamin A, E B6, B9, And B12 Deficiency

Vitamin A, E, B6, B9, and B12 deficiencies are associated with Parkinson’s Disease. Vitamin A deficiency can disrupt the normal functioning of dopamine-producing neurons in the brain, leading to the onset of motor symptoms. Vitamin E is essential for protecting cells from damage due to free radicals and may reduce oxidative stress in the brain that is associated with Parkinson’s. 

Vitamin B6 helps regulate the production of dopamine, while vitamins B9 and B12 aid in DNA synthesis, helping to restore neuron function. Studies have suggested that supplementing with these vitamins may help slow the progression of Parkinson’s Disease.14

Managing Parkinson’s Disease – Exercise

Exercise is an important factor in managing Parkinson’s disease. Regular physical activity can help reduce symptoms, improve movement and balance, and increase overall quality of life. It is recommended that people with Parkinson’s should aim for at least 150 minutes of moderate-intensity aerobic exercise per week to get the most benefit. Additionally, exercises that specifically target muscle strengthening, balance, coordination, and flexibility are important for helping to preserve movements.15

What Causes Parkinson’s Disease – Diet

While there is no evidence to suggest that specific foods cause or prevent Parkinson’s, certain dietary components are linked to the development and progression of the condition. Studies have shown that a diet rich in antioxidants and anti-inflammatory compounds can help protect against the disease.16

Consumption of foods like seeds, nuts, olive oil, fish, vegetables, and fruit is associated with lower rates of Parkinson’s Disease.17

What Causes Parkinson's Disease - Diet

What Causes Parkinson’s Disease And Can It Be Prevented

Exactly what causes Parkinson’s disease is still up for debate although genetic factors and environmental factors like pesticides, herbicides, heavy metals, and microbiome dysfunction all play a role. Exercising, consuming an organic diet, and taking in adequate vitamins is the best way to prevent this disease.

Read about what causes Alzheimer’s Disease.

References

1 Parkinson’s disease – Diagnosis and treatment – Mayo Clinic. (2023, May 26). https://www.mayoclinic.org/diseases-conditions/parkinsons-disease/diagnosis-treatment/drc-20376062

2 Bonam SR, Muller S. Parkinson’s disease is an autoimmune disease: A reappraisal. Autoimmun Rev. 2020 Dec;19(12):102684. doi: 10.1016/j.autrev.2020.102684. Epub 2020 Oct 22. PMID: 33131704.

3 Ditzel HJ. Human antibodies in cancer and autoimmune disease. Immunol Res. 2000;21(2-3):185-93. doi: 10.1385/IR:21:2-3:185. PMID: 10852116.

4 Witoelar A, Jansen IE, Wang Y, Desikan RS, Gibbs JR, Blauwendraat C, Thompson WK, Hernandez DG, Djurovic S, Schork AJ, Bettella F, Ellinghaus D, Franke A, Lie BA, McEvoy LK, Karlsen TH, Lesage S, Morris HR, Brice A, Wood NW, Heutink P, Hardy J, Singleton AB, Dale AM, Gasser T, Andreassen OA, Sharma M; International Parkinson’s Disease Genomics Consortium (IPDGC), North American Brain Expression Consortium (NABEC), and United Kingdom Brain Expression Consortium (UKBEC) Investigators. Genome-wide Pleiotropy Between Parkinson Disease and Autoimmune Diseases. JAMA Neurol. 2017 Jul 1;74(7):780-792. doi: 10.1001/jamaneurol.2017.0469. PMID: 28586827; PMCID: PMC5710535.

5 Tansey, M.G., Wallings, R.L., Houser, M.C. et al. Inflammation and immune dysfunction in Parkinson disease. Nat Rev Immunol 22, 657–673 (2022). https://doi.org/10.1038/s41577-022-00684-6

6 Sulzer D, Alcalay RN, Garretti F, Cote L, Kanter E, Agin-Liebes J, Liong C, McMurtrey C, Hildebrand WH, Mao X, Dawson VL, Dawson TM, Oseroff C, Pham J, Sidney J, Dillon MB, Carpenter C, Weiskopf D, Phillips E, Mallal S, Peters B, Frazier A, Lindestam Arlehamn CS, Sette A. T cells from patients with Parkinson’s disease recognize α-synuclein peptides. Nature. 2017 Jun 29;546(7660):656-661. doi: 10.1038/nature22815. Epub 2017 Jun 21. Erratum in: Nature. 2017 Sep 13;549(7671):292. PMID: 28636593; PMCID: PMC5626019.

7 Tansey, M.G., Wallings, R.L., Houser, M.C. et al. Inflammation and immune dysfunction in Parkinson disease. Nat Rev Immunol 22, 657–673 (2022). https://doi.org/10.1038/s41577-022-00684-6

8 Shrestha S, Parks CG, Umbach DM, Richards-Barber M, Hofmann JN, Chen H, Blair A, Beane Freeman LE, Sandler DP. Pesticide use and incident Parkinson’s disease in a cohort of farmers and their spouses. Environ Res. 2020 Dec;191:110186. doi: 10.1016/j.envres.2020.110186. Epub 2020 Sep 10. PMID: 32919961; PMCID: PMC7822498.

9 Paul KC, Ritz B. Epidemiology meets toxicogenomics: Mining toxicologic evidence in support of an untargeted analysis of pesticides exposure and Parkinson’s disease. Environ Int. 2022 Dec;170:107613. doi: 10.1016/j.envint.2022.107613. Epub 2022 Nov 9. PMID: 36395557; PMCID: PMC9897493.

10 Salkov VN, Voronkov DN, Khudoerkov RM. Rol’ rtuti i mysh’yaka v etiologii i patogeneze boleznei Parkinsona i Al’tsgeimera [The role of mercury and arsenic in the etiology and pathogenesis of Parkinson’s and Alzheimer’s diseases]. Arkh Patol. 2022;84(5):59-64. Russian. doi: 10.17116/patol20228405159. PMID: 36178224.

11 Pamphlett R, Bishop DP. Mercury is present in neurons and oligodendrocytes in regions of the brain affected by Parkinson’s disease and co-localises with Lewy bodies. PLoS One. 2022 Jan 11;17(1):e0262464. doi: 10.1371/journal.pone.0262464. PMID: 35015796; PMCID: PMC8752015.

12 Varesi A, Campagnoli LIM, Fahmideh F, Pierella E, Romeo M, Ricevuti G, Nicoletta M, Chirumbolo S, Pascale A. The Interplay between Gut Microbiota and Parkinson’s Disease: Implications on Diagnosis and Treatment. Int J Mol Sci. 2022 Oct 14;23(20):12289. doi: 10.3390/ijms232012289. PMID: 36293176; PMCID: PMC9603886.

13 Barichella M, Garrì F, Caronni S, Bolliri C, Zocchi L, Macchione MC, Ferri V, Calandrella D, Pezzoli G. Vitamin D Status and Parkinson’s Disease. Brain Sci. 2022 Jun 16;12(6):790. doi: 10.3390/brainsci12060790. PMID: 35741675; PMCID: PMC9221008.

14 Rai SN, Singh P, Steinbusch HWM, Vamanu E, Ashraf G, Singh MP. The Role of Vitamins in Neurodegenerative Disease: An Update. Biomedicines. 2021 Sep 22;9(10):1284. doi: 10.3390/biomedicines9101284. PMID: 34680401; PMCID: PMC8533313.

15 Janssen Daalen JM, Schootemeijer S, Richard E, Darweesh SKL, Bloem BR. Lifestyle Interventions for the Prevention of Parkinson Disease: A Recipe for Action. Neurology. 2022 Aug 16;99(7 Suppl 1):42-51. doi: 10.1212/WNL.0000000000200787. PMID: 35970584.

16 Knight E, Geetha T, Burnett D, Babu JR. The Role of Diet and Dietary Patterns in Parkinson’s Disease. Nutrients. 2022 Oct 25;14(21):4472. doi: 10.3390/nu14214472. PMID: 36364733; PMCID: PMC9654624.

17 Mischley LK, Lau RC, Bennett RD. Role of Diet and Nutritional Supplements in Parkinson’s Disease Progression. Oxid Med Cell Longev. 2017;2017:6405278. doi: 10.1155/2017/6405278. Epub 2017 Sep 10. PMID: 29081890; PMCID: PMC5610862.

Removing Toxins From Your Life

Removing Toxins From Your Life And From Your Body

Removing toxins from your life is the surest way to live a clean, exceptional existence that is free of disease. Toxins are chemicals or other substances that are harmful to the body. They include pollutants in the air, water, and soil. Additionally, certain foods, alcohol, drugs, and everyday household products contain harmful toxins. The presence of toxins in our environment has made it increasingly difficult to maintain a healthy lifestyle. However, there are many steps you can take to reduce your exposure to toxins and support your body’s natural detoxification processes.

Removing Toxins From Your Life

Removing toxins from our lives is important because toxic substances contribute to various chronic and debilitating diseases. Exposure to certain toxins has been linked to an increased risk of cancer, cardiovascular diseases, inflammation, and autoimmune conditions.1 In addition, these toxins can damage the central nervous system, leading to problems like headaches, fatigue, depression, anxiety, and memory loss.2 Toxic substances can also disrupt hormones, leading to hormonal imbalances with long-term health implications.3

The most critical step in removing toxins from our lives is to identify the sources of exposure and take steps to reduce or eliminate them. This might include avoiding products made with synthetic chemicals such as fragrances and dyes, eating organic food whenever possible, using natural cleaning products, avoiding air fresheners and other scented items, and reducing or eliminating exposure to environmental pollutants like smoke and smog.

Removing Toxins From Your Life

How To Identify Sources Of Toxins In Your Life

The most common types of toxins are found in the air, water, and food. While it is difficult to completely avoid these sources of toxins, there are ways to reduce their impact on your health.

Air pollution from burning fossil fuels, factory emissions, and vehicle exhaust can lead to a buildup of various pollutants in the air that we breathe. To reduce your exposure to these sources of air pollution, use an indoor air filter or better yet, relocate to an area with high-quality air.

Industrial runoff and chemicals from agricultural activity contaminate our water supply. It is important to ensure that the water you drink is safe and free from contaminants.

Read about the toxins in tap water.

Some of the most common toxins in our food supply come from pesticides, herbicides, and other additives that are used to increase yields. To reduce your exposure to these toxins, opt for organic foods whenever possible and avoid processed and packaged foods with a long list of ingredients.

Removing Toxins From Your Life By Avoiding Heavy Metals

Heavy metals are everywhere in our environment, and the most common ones include lead, mercury, arsenic, cadmium, chromium, and aluminum. These heavy metals can accumulate in our bodies over time from various sources including air pollution, soil contamination, and water supplies. Exposure to these heavy metals can have serious health effects such as neurological damage, reproductive problems, and birth defects.4 5 Therefore, it is important to identify sources of heavy metals in our lives and take steps to reduce our exposure.

One source of heavy metal toxicity that many people are unaware of is the food we eat. Foods such as canned foods, processed foods, seafood, and fish can all contain high levels of toxic metals.6 7 The best way to minimize your risk is by eating organic or locally grown food when possible. It is also important to check labels and look for foods free of heavy metals or certified as organic.

Another source of exposure to toxic metals can come from household items such as cosmetics, cleaning products, and even furniture.8 Many everyday items contain small amounts of toxins which over time can add up and cause health issues. To reduce risk, read labels carefully and opt for natural, non-toxic products whenever possible.

Read more about the toxins in cleaning products and cosmetics.

The third common source of heavy metal exposure is from the air we breathe. Air pollution from factories, vehicle exhaust, and other sources can contain high levels of toxic metals which can accumulate in the body over time.9 To reduce your exposure to airborne toxins, it is important to avoid areas with high levels of air pollution whenever possible.

Finally, water is another source of heavy metal exposure that can be difficult to avoid. Contaminated water supplies and industrial waste can contain significant amounts of toxic metals which can enter our bodies through the food we eat or through direct contact with skin.10 To reduce your risk, consume spring water or use water filters to remove as many toxins as possible.

By becoming aware of sources of toxins in your environment, you can make sure your lifestyle is as healthy and toxin-free as possible.

Read more about the toxic health effects of heavy metals.

Removing Toxins From Your Life

Removing Toxins From Your Life By Avoiding Mold

Mold is one of the most common sources of toxins. It grows in damp, poorly ventilated areas and spread spores into the air. These spores can cause a range of health problems, including nasal congestion, eye irritation, and asthma attacks. Mold produces mycotoxins which are toxic chemicals that can affect the nervous system and the immune system.11

To identify mold in your home, look for signs of water damage like discoloration or staining on walls and ceilings. You should also check for musty odors that could indicate the presence of mold. If you suspect any growth, it’s best to call an experienced professional to assess the situation and recommend a course of action to get rid of the mold and prevent future problems. It’s important to remember that mold can be hazardous and should not be handled without the proper protective gear.

Mold is just one source of toxins in your home, so it’s important to remember other potential sources as well. Check for possible pollutants like asbestos, radon gas, dust mites, lead paint chips, and pesticides from lawn care products.

Read more about the toxic health effects of mold.

Removing Toxins From Your Life By Avoiding Processed Foods, Canned Foods, And Artificial Sweeteners

Processed foods are often full of toxins like added sugars and sodium. Be sure to read ingredient labels carefully as many processed foods contain unhealthy additives such as preservatives, artificial colors, and flavors.12

Canned foods can be a convenient option but often contain potentially hazardous ingredients, such as Bisphenol A (BPA). BPA has been linked to various health conditions, including cancer and fertility problems. Choose fresh or frozen foods instead of canned whenever possible.13

Artificial sweeteners like sucralose are frequently used in many processed foods and drinks. Consumption of sucralose was recently linked with Leaky Gut Syndrome.14 

Read more about Leaky Gut Syndrome.

Many processed foods contain artificial colors and flavors that can be harmful to your health. These additives are often added to make food look or taste better but can have an array of negative effects on your body. Opt for natural foods whenever possible to avoid any potential health risks associated with these chemicals.

Removing Toxins From Your Life By Avoiding Processed Foods, Canned Foods, And Artificial Sweeteners

Cleaning Supplies And Personal Care Products

It’s important to take a look at the ingredients in cleaning supplies and personal care products. Many items like dish soap, laundry detergent, air fresheners, and makeup contain potentially hazardous chemicals that can cause allergies or other health problems. Look for natural options or products labeled “non-toxic” that are free of volatile organic compounds (VOCs), phthalates, and formaldehyde.15 16 17 Read labels carefully and avoid buying products that contain any of these ingredients. When possible, opt for eco-friendly cleaning supplies that are free of artificial fragrances, dyes, and preservatives.

It’s also important to store cleaning supplies and personal care products out of reach of children, in a cool, dry place away from sunlight. This will help reduce any potential exposure to toxins. Finally, always follow the instructions on any product you use and wear gloves when necessary. This will help reduce your risk of skin irritation or other reactions from products with harsh chemicals.

Read more about common toxins we are exposed to.

The Damage Toxins Can Do To Our Organs And Immune Systems

Toxins can do a variety of damage to our organs and immune systems. These include damage to the liver, kidneys, brain, respiratory system, cardiovascular system, gastrointestinal tract, reproductive system, and musculoskeletal system. They can also suppress the immune system by damaging important cells such as lymphocytes and macrophages that are responsible for recognizing invading pathogens.18

Toxins can also trigger autoimmune responses, where the body essentially starts to attack itself. This can lead to chronic inflammation and increases the risk of developing a variety of diseases such as diabetes, heart disease, cancer, and even allergies.19

In addition to this, exposure to toxins causes oxidative stress in our cells. This is when there is an imbalance between the production of free radicals and the body’s ability to neutralize them. This can lead to cell damage, which in turn can impair the normal function of organs and tissues. It is also believed to play a role in aging and many age-related diseases.20

Removing Toxins From Your Life And From Your Body

Choose natural cleaning products for your home. Natural products like vinegar, baking soda, and essential oils are effective alternatives to chemical cleansers. When shopping for personal care items, look for plant-based ingredients such as aloe vera and chamomile instead of synthetic fragrances and dyes.

Buy organic food whenever possible. Organic produce is grown without synthetic pesticides, herbicides, and fertilizers that contain toxins. Avoid processed foods when shopping for groceries as they often contain preservatives and other additives that may have toxic effects on your body.

Consume spring water or invest in a good water filtration system for drinking and showering with to help reduce the amount of chemicals and heavy metals in your water. Open windows or use an air purifier to improve air quality. Change your air filter regularly and vacuum often to reduce dust and other irritants in the home.

Use green laundry detergents and natural fabric softeners that are free from harsh chemical agents. Choose furniture, carpets, and paint with low VOCs to reduce indoor air pollution.

Removing Toxins From Your Life And From Your Body

Removing Toxins From Your Life And From Your Body

Removing toxins from your life is the best way to reduce the probability of developing diseases like autoimmune conditions. While it is impossible to avoid all toxins, focusing on living a healthy lifestyle can go a long way in ensuring good health.

Read more about detoxing your body.

References

1 Kharrazian D. Exposure to Environmental Toxins and Autoimmune Conditions. Integr Med (Encinitas). 2021 Apr;20(2):20-24. PMID: 34377090; PMCID: PMC8325494.

2 Paulson GW. Environmental effects on the central nervous system. Environ Health Perspect. 1977 Oct;20:75-96. doi: 10.1289/ehp.772075. PMID: 202447; PMCID: PMC1637320.

3 Yilmaz B, Terekeci H, Sandal S, Kelestimur F. Endocrine disrupting chemicals: exposure, effects on human health, mechanism of action, models for testing and strategies for prevention. Rev Endocr Metab Disord. 2020 Mar;21(1):127-147. doi: 10.1007/s11154-019-09521-z. PMID: 31792807.

4 Witkowska D, Słowik J, Chilicka K. Heavy Metals and Human Health: Possible Exposure Pathways and the Competition for Protein Binding Sites. Molecules. 2021 Oct 7;26(19):6060. doi: 10.3390/molecules26196060. PMID: 34641604; PMCID: PMC8511997.

5 Fu Z, Xi S. The effects of heavy metals on human metabolism. Toxicol Mech Methods. 2020 Mar;30(3):167-176. doi: 10.1080/15376516.2019.1701594. Epub 2019 Dec 17. PMID: 31818169.

6 Massadeh AM, Al-Massaedh AAT. Determination of heavy metals in canned fruits and vegetables sold in Jordan market. Environ Sci Pollut Res Int. 2018 Jan;25(2):1914-1920. doi: 10.1007/s11356-017-0611-0. Epub 2017 Nov 4. PMID: 29103121.

7 Hashim R, Song TH, Muslim NZ, Yen TP. Determination of Heavy Metal Levels in Fishes from the Lower Reach of the Kelantan River, Kelantan, Malaysia. Trop Life Sci Res. 2014 Dec;25(2):21-39. PMID: 27073597; PMCID: PMC4814144.

8 Center for Food Safety and Applied Nutrition. (2022, November 22). Limiting Lead in Lipstick and Other Cosmetics. U.S. Food And Drug Administration. https://www.fda.gov/cosmetics/cosmetic-products/limiting-lead-lipstick-and-other-cosmetics

9 Yuan Y, Wu Y, Ge X, Nie D, Wang M, Zhou H, Chen M. In vitro toxicity evaluation of heavy metals in urban air particulate matter on human lung epithelial cells. Sci Total Environ. 2019 Aug 15;678:301-308. doi: 10.1016/j.scitotenv.2019.04.431. Epub 2019 Apr 30. PMID: 31075597.

10 Rehman K, Fatima F, Waheed I, Akash MSH. Prevalence of exposure of heavy metals and their impact on health consequences. J Cell Biochem. 2018 Jan;119(1):157-184. doi: 10.1002/jcb.26234. Epub 2017 Aug 2. PMID: 28643849.

11 Tessier, L. (2020, February 10). Endocrine Impacts of Mycotoxins. Naturopathic Doctor News and Review. https://ndnr.com/endocrinology/endocrine-impacts-of-mycotoxins/

12 Fuhrman J. The Hidden Dangers of Fast and Processed Food. Am J Lifestyle Med. 2018 Apr 3;12(5):375-381. doi: 10.1177/1559827618766483. PMID: 30283262; PMCID: PMC6146358.

13 Ma Y, Liu H, Wu J, Yuan L, Wang Y, Du X, Wang R, Marwa PW, Petlulu P, Chen X, Zhang H. The adverse health effects of bisphenol A and related toxicity mechanisms. Environ Res. 2019 Sep;176:108575. doi: 10.1016/j.envres.2019.108575. Epub 2019 Jul 3. PMID: 31299621.

14 Méndez-García LA, Bueno-Hernández N, Cid-Soto MA, De León KL, Mendoza-Martínez VM, Espinosa-Flores AJ, Carrero-Aguirre M, Esquivel-Velázquez M, León-Hernández M, Viurcos-Sanabria R, Ruíz-Barranco A, Cota-Arce JM, Álvarez-Lee A, De León-Nava MA, Meléndez G, Escobedo G. Ten-Week Sucralose Consumption Induces Gut Dysbiosis and Altered Glucose and Insulin Levels in Healthy Young Adults. Microorganisms. 2022 Feb 14;10(2):434. doi: 10.3390/microorganisms10020434. PMID: 35208888; PMCID: PMC8880058.

15 Wen H, Yuan L, Wei C, Zhao Y, Qian Y, Ma P, Ding S, Yang X, Wang X. Effects of combined exposure to formaldehyde and benzene on immune cells in the blood and spleen in Balb/c mice. Environ Toxicol Pharmacol. 2016 Jul;45:265-73. doi: 10.1016/j.etap.2016.05.007. Epub 2016 May 9. PMID: 27343751.

16 Dai H, Jing S, Wang H, Ma Y, Li L, Song W, Kan H. VOC characteristics and inhalation health risks in newly renovated residences in Shanghai, China. Sci Total Environ. 2017 Jan 15;577:73-83. doi: 10.1016/j.scitotenv.2016.10.071. Epub 2016 Nov 4. PMID: 27817926.

17 Koniecki D, Wang R, Moody RP, Zhu J. Phthalates in cosmetic and personal care products: concentrations and possible dermal exposure. Environ Res. 2011 Apr;111(3):329-36. doi: 10.1016/j.envres.2011.01.013. Epub 2011 Feb 18. PMID: 21315328.

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19 Furman D, Campisi J, Verdin E, Carrera-Bastos P, Targ S, Franceschi C, Ferrucci L, Gilroy DW, Fasano A, Miller GW, Miller AH, Mantovani A, Weyand CM, Barzilai N, Goronzy JJ, Rando TA, Effros RB, Lucia A, Kleinstreuer N, Slavich GM. Chronic inflammation in the etiology of disease across the life span. Nat Med. 2019 Dec;25(12):1822-1832. doi: 10.1038/s41591-019-0675-0. Epub 2019 Dec 5. PMID: 31806905; PMCID: PMC7147972.

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