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Do Heavy Metals Affect The Thyroid?

Heavy Metals Affect The Thyroid Causing Downstream Symptoms

The number of ways heavy metals affect the thyroid is astounding. The thyroid gland plays a crucial role in regulating metabolism and other essential bodily functions. Chronic exposure to heavy metals such as lead, mercury, cadmium, and arsenic has been linked to thyroid dysfunction, leading to various health issues.

The Function Of The Thyroid Gland

The thyroid gland plays a crucial role in maintaining our overall health and well-being. It is responsible for producing hormones that regulate essential bodily functions such as metabolism, growth and development, energy levels, and body temperature. The two main hormones produced by the thyroid gland are triiodothyronine (T3) and thyroxine (T4), which are synthesized using iodine from the food we consume.

Aside from its primary function of hormone production, the thyroid gland also acts as a key player in our immune system. It helps to protect our body against infections and diseases by producing antibodies that fight off harmful invaders.

Furthermore, the thyroid gland works closely with other endocrine glands in the body to maintain a delicate balance of hormones. This intricate system ensures that our body functions optimally, allowing us to lead a healthy and active lifestyle.1

How Heavy Metals Affect The Thyroid

The negative impact of heavy metals on thyroid health cannot be overstated. Among the most common culprits are mercury, lead, and cadmium, as well as aluminum. These toxic substances not only interfere with the production and absorption of thyroid hormones but also cause damage to the thyroid gland and hypothalamus.

It is crucial to minimize exposure to these heavy metals in order to maintain a healthy functioning thyroid.  So, it’s important to take preventive measures such as avoiding contaminated water sources, opting for organic foods, and reducing the use of products containing heavy metals. We will discuss how to remove heavy metals from the body later.2

Heavy Metals Affect The Thyroid Causing Downstream Symptoms

Heavy Metals Affect The Thyroid – Mercury

Mercury is a highly toxic element that can have detrimental effects on the body, especially on the thyroid gland. Once it enters the body, mercury can cause inflammation and damage to this important gland. This can result in various thyroid conditions, including dysfunction and imbalances in hormone levels.

One of the ways mercury interferes with the thyroid is by binding to essential proteins needed for thyroid hormone production. This disruption can lead to an underactive thyroid and contribute to symptoms such as fatigue, weight gain, and depression.

Moreover, exposure to mercury can trigger autoimmune reactions within the body. Autoimmune diseases occur when the immune system mistakenly attacks healthy cells instead of foreign invaders. In this case, mercury may be a contributing factor to conditions such as Hashimoto’s thyroiditis or Graves’ disease, which are both linked to thyroid dysfunction.

In addition, mercury also impairs the conversion of the inactive T4 hormone to its active form, T3. This disruption can result in hypothyroidism and its associated symptoms. Therefore, it is important to minimize exposure to mercury and other toxins in order to protect the health of our thyroid gland.3

Heavy Metals Affect The Thyroid – Lead

According to recent studies, lead has been identified as a potential disruptor in the production of thyroid hormones. Much like mercury, this toxic element is known to affect thyroid function by impeding the conversion of T4 into its active form, T3. Furthermore, there is evidence linking lead exposure to autoimmune disorders such as Hashimoto’s thyroiditis and Grave’s disease.4

Heavy Metals Affect The Thyroid – Cadmium

Cadmium, a toxic heavy metal, has been linked to various adverse health effects in humans. One of the most concerning is its ability to cause hyperthyroidism, which is characterized by an overactive thyroid gland. This occurs because cadmium can mimic the behavior of iodine in the body, leading to an excess production of thyroid hormones.5

Heavy Metals Affect The Thyroid – Aluminum

According to various studies, the presence of aluminum has been linked to an increased risk of developing thyroid nodules. This metal can commonly be found in personal care products including antiperspirants that are applied topically. The absorption of aluminum through the skin can lead to its accumulation in the body, causing harm to vital organs such as the thyroid gland.

Aside from personal care items, aluminum can also be found in processed foods, cookware, and even tap water. This is due to contamination from industrial processes, indicating that our exposure to this toxic element is constant and often unknown. It is important for individuals to be aware of these sources of aluminum and take steps to minimize their exposure in order to protect their health.6

Mercury And Aluminum Combined Significantly Affects The Thyroid

The harmful effects of mercury and aluminum on the thyroid gland have long been established. However, recent studies have shown that these two metals can have a synergistic effect when present in the body at the same time.

Synergistic effects refer to the phenomenon where two or more substances combine to produce a greater effect than if they were used alone. In other words, when mercury and aluminum are present together in the body, their impact on thyroid function is amplified.

One major reason for this is that both mercury and aluminum have similar mechanisms of action within the body. They both disrupt important processes that are crucial for proper thyroid function, such as the production and regulation of hormones.

Additionally, both metals are able to cross the blood-brain barrier and accumulate in the hypothalamus, a key area responsible for regulating hormone levels in the body. This means that when both mercury and aluminum are present, they can cause problems upstream in the hypothalamus, further contributing to thyroid dysfunction.7

Heavy Metals And Their Connection To Inflammation-Related Health Issues

Cellular membrane inflammation, triggered by heavy metals in our body, is a major contributor to various degenerative diseases. This type of inflammation has the ability to alter the shape of hormone receptors, hindering them from effectively relaying messages throughout the cell. Such changes can result in thyroid hormone resistance, a condition that affects not only thyroid hormones but also other important hormones like insulin, estrogen, testosterone, and leptin.

Moreover, it has been discovered that this type of cellular membrane inflammation is primarily caused by toxins present in our environment. These toxins can disrupt the normal functioning of our body’s cells and lead to various health issues. It is crucial to minimize exposure to such toxins in order to prevent and manage hormone resistance and related conditions.8 9

Glyphosate And Heavy Metals – A Dangerous Combination

The use of glyphosate, the primary ingredient in Roundup, has been linked to a concerning effect on the blood-brain barrier (BBB). This crucial barrier acts as a gatekeeper for the brain, controlling what can enter and exit. However, studies have shown that glyphosate can compromise this barrier’s proteins, making it more permeable. This allows harmful substances such as mercury and aluminum to enter the brain with greater ease. As a result, there is an increased accumulation of toxic heavy metals in the hypothalamus region of the brain.10

The Connection Between The Hypothalamus And The Thyroid

Thyroid conditions are frequently linked to dysfunctions in the hypothalamus. As someone who has experienced this firsthand, I can attest to how debilitating it can be. When I was 34 years old, I suddenly fell extremely ill without any apparent cause. The first sign for me was an overwhelming sense of fatigue and a noticeable decrease in muscle mass. This was confusing to me since I was actively training for mountain bike competitions at the time.

Along with these symptoms, I also struggled with brain fog, anxiety, irritability, and disrupted sleep patterns on a daily basis. But perhaps the most unexpected health issue that arose from this condition was multiple chemical sensitivity (MCS). It became so severe that I couldn’t tolerate even a minute of my own children crying, and the mere scent of cologne would send me into a frenzy.

After experiencing a range of symptoms that seemed to align with either thyroid dysfunction or adrenal fatigue, I sought medical help and underwent multiple blood tests. To my surprise, the results showed that I was seemingly healthy. However, as time went on, my symptoms only worsened, leaving me frustrated and desperate for answers.

I turned to extensive research in an attempt to understand what could be causing my mysterious illness. Despite considering various possibilities, one potential cause kept resurfacing: mercury toxicity. Yet, every time I had a blood test done, it showed no signs of any issues related to mercury.

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It wasn’t until I consulted with a top endocrinologist that the possibility of mercury toxicity was brought up again. He explained that chronic accumulation of mercury in the hypothalamus, over the course of many years, could lead to various health problems without showing up on standard blood tests. Suddenly, everything clicked for me – I had been using contact lens solution containing mercury for decades and had silver dental fillings with high levels of mercury.

The endocrinologist’s explanation made perfect sense – as heavy metals build up in the hypothalamus, it disrupts its function as the control center of the endocrine system. Like a busy airport without a control tower, this disarray can result in hormone imbalances and contribute to conditions such as thyroid dysfunction. My journey towards understanding my illness had finally led me to the cause – mercury toxicity.

How I Developed The 5Rs To Address The Root Cause Of Heavy Metal Toxicity

After realizing that mercury and other toxins were causing my sickness, I knew I needed to take immediate action to remove them from my body and brain. This led me to develop the 5Rs method, which focuses on cellular detoxification as the key to addressing thyroid conditions.

As part of the Pompa Program, the brain phase specifically targets heavy metals in the hypothalamus, helping to restore endocrine function and address thyroid issues at their core. Through thorough research and personal experience, I have found that this approach is crucial in achieving optimal thyroid health.

If you want to learn more about how the 5Rs method can help you detoxify and improve your thyroid health, listen in to the my free webinar.

References

1 Thyroid disease: assessment and management. London: National Institute for Health and Care Excellence (NICE); 2019 Nov 20. (NICE Guideline, No. 145.) Available from: https://www.ncbi.nlm.nih.gov/books/NBK550859/

2 Chen A, Kim SS, Chung E, Dietrich KN. Thyroid hormones in relation to lead, mercury, and cadmium exposure in the National Health and Nutrition Examination Survey, 2007-2008. Environ Health Perspect. 2013 Feb;121(2):181-6. doi: 10.1289/ehp.1205239. Epub 2012 Nov 16. PMID: 23164649; PMCID: PMC3569681.

3 Pamphlett R, Doble PA, Bishop DP. Mercury in the human thyroid gland: Potential implications for thyroid cancer, autoimmune thyroiditis, and hypothyroidism. PLoS One. 2021 Feb 9;16(2):e0246748. doi: 10.1371/journal.pone.0246748. PMID: 33561145; PMCID: PMC7872292.

4 Rivera-Buse JE, Patajalo-Villalta SJ, Donadi EA, Barbosa F Junior, Magalhães PKR, Maciel LMZ. Impact of lead exposure on the thyroid glands of individuals living in high- or low-lead exposure areas. Medicine (Baltimore). 2023 Mar 24;102(12):e33292. doi: 10.1097/MD.0000000000033292. PMID: 36961188; PMCID: PMC10036069.

5 Buha A, Matovic V, Antonijevic B, Bulat Z, Curcic M, Renieri EA, Tsatsakis AM, Schweitzer A, Wallace D. Overview of Cadmium Thyroid Disrupting Effects and Mechanisms. Int J Mol Sci. 2018 May 17;19(5):1501. doi: 10.3390/ijms19051501. PMID: 29772829; PMCID: PMC5983752.

6 Li A, Zhou Q, Mei Y, Zhao J, Zhao M, Xu J, Ge X, Li Y, Li K, Yang M, Xu Q. Thyroid disrupting effects of multiple metals exposure: Comprehensive investigation from the thyroid parenchyma to hormonal function in a prospective cohort study. J Hazard Mater. 2023 Oct 5;459:132115. doi: 10.1016/j.jhazmat.2023.132115. Epub 2023 Jul 22. PMID: 37499494.

7 Alexandrov PN, Pogue AI, Lukiw WJ. Synergism in aluminum and mercury neurotoxicity. Integr Food Nutr Metab. 2018 May;5(3):10.15761/IFNM.1000214. doi: 10.15761/IFNM.1000214. Epub 2018 Apr 13. PMID: 29938114; PMCID: PMC6013271.

8 Haidar Z, Fatema K, Shoily SS, Sajib AA. Disease-associated metabolic pathways affected by heavy metals and metalloid. Toxicol Rep. 2023 Apr 24;10:554-570. doi: 10.1016/j.toxrep.2023.04.010. PMID: 37396849; PMCID: PMC10313886.

9 Straub RH. Interaction of the endocrine system with inflammation: a function of energy and volume regulation. Arthritis Res Ther. 2014 Feb 13;16(1):203. doi: 10.1186/ar4484. PMID: 24524669; PMCID: PMC3978663.

10 Costas-Ferreira C, Durán R, Faro LRF. Toxic Effects of Glyphosate on the Nervous System: A Systematic Review. Int J Mol Sci. 2022 Apr 21;23(9):4605. doi: 10.3390/ijms23094605. PMID: 35562999; PMCID: PMC9101768.

Disclaimer: All rights reserved. Information provided is for general purposes and not intended to provide medical advice, diagnosis, or treatment. Consult your healthcare professional for medical concerns. About Dr. Pompa

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